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    Chapter

    The Influence of Folic Acid Content of Media on TPA-Induced Transformation of JB6 Cells

    The influence of folates on carcinogenesis has been studied for many years, but there are still few published data about the effects of folates on carcinogenic events in cells. The JB6 murine epidermal cell li...

    Y. W. Chien, C. W. Prince, R. J. Hine in Diet and Cancer (1994)

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    Article

    Methotrexate therapy in rheumatoid arthritis patients diminishes lectin-induced mononuclear cell proliferation

    Methotrexate (MTX) is an anti-folate drug used in cancer chemotherapy because of its anti-proliferative effects. However, it is unclear whether the anti-proliferative effects of MTX contribute to the efficacy ...

    R. J. Hine, M. P. Everson, J. M. Hardin, S. L. Morgan in Rheumatology International (1990)