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  1. Article

    Open Access

    Lactate activates hypothalamic POMC neurons by intercellular signaling

    Previous studies indicate that the activity of hypothalamic POMC neurons can be regulated by glucose via intracellular mechanisms, but its regulation by lactate is poorly understood. In addition to its energet...

    P. Órdenes, P. S. Villar, E. Tarifeño-Saldivia, M. Salgado in Scientific Reports (2021)

  2. Article

    Open Access

    PPARβ/δ-dependent MSC metabolism determines their immunoregulatory properties

    Mesenchymal stem cell (MSC)-based therapy is being increasingly considered a powerful opportunity for several disorders based on MSC immunoregulatory properties. Nonetheless, MSC are versatile and plastic cell...

    R. A. Contreras-Lopez, R. Elizondo-Vega, M. J. Torres in Scientific Reports (2020)