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A site-resolved two-dimensional quantum simulator with hundreds of trapped ions
A large qubit capacity and an individual readout capability are two crucial requirements for large-scale quantum computing and simulation1. As one of the leading physical platforms for quantum information process...
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The relative contributions of iron and aluminum oxides to ferrocyanide retention in soils: a comparative study
Ferrocyanide adsorption onto goethite and gibbsite is normally regarded as an important reaction in cyanide-contaminated soil systems over a broad range of environmental conditions. However, the contribution o...
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Article
Author Correction: A fast radio burst source at a complex magnetized site in a barred galaxy
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A fast radio burst source at a complex magnetized site in a barred galaxy
Fast radio bursts (FRBs) are highly dispersed, millisecond-duration radio bursts1–3. Recent observations of a Galactic FRB4–8 suggest that at least some FRBs originate from magnetars, but the origin of cosmologic...
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Article
Structural Characterization and Magnetic Properties of SrCo2Fe16O27 Hexaferrite Synthesized by Citric Acid Sol-Gel Method
The W -type SrCo2Fe16O27 (SCFO) hexagonal ferrite samples were prepared by the sol-gel method using metal nitrate as raw material, citric acid as complexing agent, and water as solvent. The effects of different s...
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Article
Open AccessFOXC1 overexpression is a marker of poor response to anthracycline-based adjuvant chemotherapy in sporadic triple-negative breast cancer
Because of its aggressive characteristics and poor prognosis, triple-negative breast cancer (TNBC) has become a hot topic in cancer research. Chemotherapy is currently the only treatment for patients with TNBC...
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Suppression of intestinal tumors by targeting the mitotic spindle of intestinal stem cells
Human colorectal cancer is often initiated by the aberrant activation of Wnt signaling, notably following adenomatous polyposis coli (Apc) inactivation. Recent studies identified adult intestinal stem cells (I...
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Health-related quality-of-life improvements during 98 weeks of infliximab therapy in patients with plaque-type psoriasis in real-world practice
We evaluated the effect of plaque-type psoriasis on health-related quality of life (HRQoL) of patients who received infliximab (IFX) in real-world clinical settings.
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Article
JMJD3 promotes SAHF formation in senescent WI38 cells by triggering an interplay between demethylation and phosphorylation of RB protein
Primary human fibroblasts undergoing oncogene-induced or replicative senescence are known to form senescence-associated heterochromatin foci (SAHF), which can stabilize the state of senescence. The retinoblast...
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Article
A small compound targeting TACC3 revealed its different spatiotemporal contributions for spindle assembly in cancer cells
The mitotic spindle is assembled by the coordinated action of centrosomes and kinetochore microtubules. An evolutionally conserved protein family, transforming acidic coiled-coil (TACC), has been shown to be i...
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Open AccessLincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasis
LncRNAs have critical roles in various biological processes ranging from embryonic development to human diseases, including cancer progression, although their detailed mechanistic functions remain illusive. Th...
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Overexpressed transcription factor FOXM1 is a potential diagnostic and adverse prognostic factor in postoperational gastric cancer patients
In the present study, we intend to detect the expression of Forkhead box transcription (FOXM1) in gastric cancer tissues and cell lines, and analyze the correlation between FOXM1 expression and clinic-patholog...
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Space heating and hot water demand analysis of dwellings connected to district heating scheme in UK
To achieve CO2 emissions reductions, the UK Building Regulations require developers of new residential buildings to calculate expected CO2 emissions arising from their energy consumption using a methodology such ...
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Disruption of Tacc3 function leads to in vivo tumor regression
The formation of the bipolar spindle is responsible for accurate chromosomal segregation during mitosis. The dynamic instability of microtubules has an important role in this process, and has been shown to be ...
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Absorption coefficient measurement of high-resistivity germanium at 2.52 THz by Brewster’s angle method
Brewster’s angle method was adopted to measure the absorption coefficient of a set of high-resistivity germanium samples at 2.52 THz in this paper. Numerical simulations were firstly carried out to evaluate th...
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Open AccessOnset of action of loratadine/montelukast combination in subjects with seasonal allergic rhinitis in the environmental exposure unit
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Brewster’s angle method for absorption coefficient measurement of high-resistivity silicon based on CW THz laser
A simple method for measuring the absorption coefficient of low absorbing materials using CW THz laser was put forward. The method was based on transmittance measurements at the Brewster’s angle for p-polarize...
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Combined anti-inflammatory tritherapy using a novel small interfering RNA lipoplex successfully prevents and cures mice of arthritis
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Prevention of lung cancer progression by bexarotene in mouse models
Bexarotene (Targretin®, Ligand Pharmaceuticals Inc.) is a synthetic high-affinity RXR receptor agonist with limited affinity for RAR receptors. Bexarotene has shown efficacy in a phase I/II trial of non-small-cel...
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Article
Thermal sprayed nanostructured WC/Co hardcoatings
Hardcoatings of WC/Co, produced by high-velocity oxy-fuel (HVOF) and air plasma spray (APS) deposition, have been studied. During HVOF deposition, nanostructured powder experiences more decarburization than co...