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  1. No Access

    Article

    Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer

    Proteolysis targeting chimeric molecules (Protacs) target proteins for destruction by exploiting the ubiquitin-dependent proteolytic system of eukaryotic cells. We designed two Protacs that contain the peptide...

    A Rodriguez-Gonzalez, K Cyrus, M Salcius, K Kim, C M Crews, R J Deshaies… in Oncogene (2008)

  2. No Access

    Chapter and Conference Paper

    Soluble and Membrane-Associated Factors Required for Protein Translocation into the Yeast Endoplasmic Reticulum

    A genetic approach aimed at defining molecules that participate in protein translocation across the membrane of the endoplasmic reticulum (ER) has led to the identification of three new genes. Mutant cells tha...

    R. J. Deshaies, A. Eun, B. D. Koch, J. A. Rothblatt… in Dynamics and Biogenesis of Membranes (1990)