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Open AccessNutrient stress alters the glycosylation status of LGR5 resulting in reduced protein stability and membrane localisation in colorectal tumour cells: implications for targeting cancer stem cells
LGR5 is an important marker of intestinal stem cells and performs its vital functions at the cell membrane. Despite the importance of LGR5 to both normal and cancer stem cell biology, it is not known how micro...
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Article
Heterocyclic amines and genotype of N-acetyltransferases as risk factors for prostate cancer
A variety of carcinogenic heterocyclic amines are produced during the cooking of meat at high temperatures. These carcinogens are metabolized by N-acetyltransferases (NAT), which are polymorphic in the population...
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Article
Colonic volvulus in the spinal cord injured patient
At the Prince Henry Hospital between 1970 and 1987, 8 cases of colonic volvulus were diagnosed in spinal cord injured (SCI) patients. This represents an incidence of 2.6% of SCI patients being treated at the h...
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Pregnancy by gamete intrafallopian transfer (GIFT) with sperm aspirated from the vaso-epididymal junction of spinal injured man
A case is reported of pregnancy resulting from oocytes retrieved by transvaginal ultrasound with sperm obtained by aspiration of the vasa deferentia close to the epididymis of a quadriplegic man and replaced b...
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The relation between electrical resistivity and particulate volume fraction in aluminium alloy metal-matrix composites
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Bracing of thoracic and lumbar spine fractures
A prospective study of the non-operative management of 33 thoracic and lumbar fractures and dislocations was undertaken examining factors such as duration of bed rest and brace prescription. Outcome was assess...
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Article
A new pressure measuring system for cushions and beds—with a review of the literature
An interface pressure measuring device for the assessment of subject-cushion interface pressures at ten points has been described. Preliminary trials using 12 healthy subjects on four cushions and three spinal...
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Article
The ecology of temperate salt-marsh fucoids. II. In situ growth of transplanted Ascophyllum nodosum ecads
Growth, in terms of length, weight, and number of branches and/or dichotomies, in transplanted specimens of Ascophyllum nodosum ecad scorpioides in a temperate salt marsh is described. The ecad scorpioides, when ...
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Article
Photosynthesis and respiration of exposed salt-marsh fucoids
Photosynthesis and respiration of the salt-marsh fucoids Ascophyllum nodosum ecad scorpioides and Fucus vesiculosus were investigated using an infrared CO2 gas analyzer under a variety of light intensities, tempe...
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Article
Lethal and mutagenic effects of nitrosoguanidine on synchronizedChlamydomonas
The lethal and mutagenic effects of 5 μg/ml N-methyl-N′-nitro-N-nitrosoguanidine (MNNG) were maximal during the nuclear S-period of synchronously grownChlamydomonas reinhardtii. This was revealed by a 50% drop in...
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Article
Photosynthesis in whole plants of Chondrus crispus
Photosynthesis in whole plants of Chondrus crispus Stackhouse was measured by 14C uptake under various light intensities and temperature regimes. In plants collected from waters of 6° to 7°C, photosynthesis did n...
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Studies on the buoyant density of a feline calicivirus
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Meteorology and Supersonic Flight*
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Centrifugal evaporation of organic solvents from a series of solutions
A centrifugal vacuum evaporator designed for the evaporation of organic solvents from a series of solutions has been fabricated and tested. The rotor is driven by a spinning magnetic field resulting from rotat...
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Short Reviews
An Introduction to Atmospheric Physics
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Application of Radar to Meteorology: Conference in Montreal
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Low-Level Atmospheric Ducts
IN a communication in Nature1, I suggested an explanation for the occurrence of low-level atmospheric ducts over the sea, which had been reported by McPetrie and Starkey2 in conditions of strong winds. It was sug...
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Radar Observation of Heavy Rain
IN view of the article on this subject which appeared in Nature of March 5, p. 372, it may be stated that the systematic exploration of clouds and rainfall by means of radar has been proceeding actively in Great ...
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Low-Level Atmospheric Ducts
IN a recent communication in Nature1, McPetrie and Starnecki have directed attention to the presence of atmospheric ducts at or close to the sea surface. The presence of low atmospheric ducts when the air at 100 ...
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Article
Percy Sladen Expedition to Lake Huleh
THE Percy Sladen Expedition to Lake Huleh, Palestine, consisting of the present writers, has now returned. Biological investigations have been carried out during the greater part of the period August-December ...
