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Article
Open AccessTrends of mortality rate in patients with congenital heart defects in Germany—analysis of nationwide data of the Federal Statistical Office of Germany
Congenital heart defects (CHD) are still associated with an increased morbidity and mortality. The aim of this study was to analyze trends of mortality rates in patients with CHD between 1998 and 2018 in Germany.
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Article
Open AccessSARS-CoV-2 sero-immunity and quality of life in children and adolescents in relation to infections and vaccinations: the IMMUNEBRIDGE KIDS cross-sectional study, 2022
The study evaluates the effects on sero-immunity, health status and quality of life of children and adolescents after the upsurge of the Omicron variant in Germany.
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Article
Open AccessComparing SARS-CoV-2 variants among children and adolescents in Germany: relative risk of COVID-19-related hospitalization, ICU admission and mortality
SARS-CoV-2 infections cause COVID-19 and have a wide spectrum of morbidity. Severe disease courses among children are rare. To date, data on the variability of morbidity in relation to variant of concern (VOC)...
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Article
Open AccessGrowth patterns in children and adolescents with cerebral palsy from Argentina and Germany
To analyze growth patterns of children with CP between countries; to examine differences in growth; and to assess the fit of growth charts. Cross-sectional study in children with CP from 2 to 19 years old, 399...
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Article
Open AccessRisk for severe outcomes of COVID-19 and PIMS-TS in children with SARS-CoV-2 infection in Germany
Although children and adolescents have a lower burden of SARS-CoV-2-associated disease compared to adults, assessing the risk for severe outcomes among SARS-CoV-2-infected children remains difficult due to a h...
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Article
Open AccessCognitive disorders in childhood epilepsy: a comparative longitudinal study using administrative healthcare data
The study aimed to assess the risk of cognitive impairment in patients with epilepsy, the impact of age of epilepsy onset on cognition and the temporal relationship of epilepsy onset and intellectual impairment.
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Article
Open AccessTotal health insurance costs in children with a migraine diagnosis compared to a control group
Health care costs of migraine constitute a major issue in health economics. Several publications analyzed health care costs for adult migraine patients, based on questionnaires or secondary (health insurance) ...
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Article
Open AccessSafety and effectiveness of acellular pertussis vaccination during pregnancy: a systematic review
Infants < 3 months of age are at highest risk for develo** severe complications after pertussis. The majority of pregnant women has low concentrations of pertussis-specific antibodies and thus newborns are i...
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Article
Open AccessCorrection to: Incidence of tuberous sclerosis and age at first diagnosis: new data and emerging trends from a national, prospective surveillance study
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Article
Open AccessIncidence of tuberous sclerosis and age at first diagnosis: new data and emerging trends from a national, prospective surveillance study
Tuberous Sclerosis Complex (TSC) is a rare multisystem disorder. In 2012 diagnostic criteria for TSC were revised. However, data on the incidence of TSC are limited.
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Article
Long-lasting cough in an adult German population: incidence, symptoms, and related pathogens
Studies of the incidence of pertussis in adults have shown that it accounts for only 5–15% cases of prolonged coughing. We assessed the burden of suffering related to prolonged coughing and tried to identify f...
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Article
Open AccessNeighbourhood socioeconomic context, individual socioeconomic position, and overweight in young children: a multilevel study in a large German city
The context of the close neighbourhood environment in which children live has gained increasing attention in epidemiological research. This study aimed to investigate if contextual neighbourhood socioeconomic ...
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Article
Open AccessMethods for Health Economic Evaluation of Vaccines and Immunization Decision Frameworks: A Consensus Framework from a European Vaccine Economics Community
Incremental cost-effectiveness and cost-utility analyses [health economic evaluations (HEEs)] of vaccines are routinely considered in decision making on immunization in various industrialized countries. While...
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Article
Background Paper for the update of meningococcal vaccination recommendations in Germany: use of the serogroup B vaccine in persons at increased risk for meningococcal disease
In December 2013 Bexsero® became available in Germany for vaccination against serogroup B meningococci (MenB). In August 2015 the German Standing Committee on Vaccination (STIKO) endorsed a recommendation for ...
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Article
Excessive gestational weight gain prior to glucose screening and the risk of gestational diabetes: a meta-analysis
Excessive gestational weight gain (GWG) may be a risk factor for gestational diabetes mellitus (GDM). We aimed to study the association between excessive GWG (defined according to Institute of Medicine recomme...
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Article
Open AccessMigraine and tension type headache in adolescents at grammar school in Germany – burden of disease and health care utilization
Tension-type headache and migraine are among the most prevalent chronic disorders in children/adolescents. Data on health care utilization for headache in this age group, however, are sparse.
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Article
Open AccessEffects of trimester-specific and total gestational weight gain on children’s anthropometrics
Gestational weight gain (GWG) has been shown to be a risk factor for overweight in offspring.
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Article
Open AccessHigh diagnostic stability of confirmed migraine and confirmed tension-type headache according to the ICHD-3 beta in adolescents
Stable headache diagnosis classification is a prerequisite for identification of headache type specific risk factors. Does the stability of a headache diagnosis over time vary between migraine and tension-type...
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Article
Open AccessUnderstanding interventions for improving routine immunization coverage in children in low- and middle-income countries: a systematic review protocol
Virtually all low- and middle-income countries are dependent on the World Health Organization’s Expanded Program on Immunization for delivery of vaccines to children. The Expanded Program on Immunization deliv...
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Article
Open AccessIdentified risk factors and adolescents’ beliefs about triggers for headaches: results from a cross-sectional study
Although there are few studies on adolescents’ beliefs about triggers of headache, none of these compared the associations between perceived and observed triggers. This study aimed at comparing the prevalence ...
