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Article
Incidence of SCID in Germany from 2014 to 2015 an ESPED* Survey on Behalf of the API*** Erhebungseinheit für Seltene Pädiatrische Erkrankungen in Deutschland (German Paediatric Surveillance Unit) ** Arbeitsgemeinschaft Pädiatrische Immunologie
Severe combined immunodeficiencies (SCID) are a heterogeneous group of fatal genetic disorders, in which the immune response is severely impaired. SCID can be cured if diagnosed early. We aim to determine the ...
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Article
Open AccessSafety and effectiveness of acellular pertussis vaccination during pregnancy: a systematic review
Infants < 3 months of age are at highest risk for develo** severe complications after pertussis. The majority of pregnant women has low concentrations of pertussis-specific antibodies and thus newborns are i...
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Article
Long-lasting cough in an adult German population: incidence, symptoms, and related pathogens
Studies of the incidence of pertussis in adults have shown that it accounts for only 5–15% cases of prolonged coughing. We assessed the burden of suffering related to prolonged coughing and tried to identify f...
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Article
Open AccessEffect of heptavalent pneumococcal conjugate vaccination on invasive pneumococcal disease in preterm born infants
Evidence for protection of preterm born infants from invasive pneumococcal disease (IPD) by 7-valent pneumococcal conjugate vaccination (PCV7) is relatively sparse. Data from randomized trials is based on rela...
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Article
Open AccessInvasive Haemophilus influenzaeinfections in Germany: impact of non-type b serotypes in the post-vaccine era
Haemophilus influenzae type b (Hib) vaccination led to a significant decrease in invasive bacterial infections in children. The aim of this study was to assess a potential shift to more non-type b invasive inf...