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Article
Comparison of the cytokines levels in aqueous humor in vitrectomized eyes versus non-vitrectomized eyes with diabetic macular edema
This study was conducted to compare concentrations of VEGF family growth factors, inflammation-related factors, and adhesion molecules in the aqueous humor of eyes with diabetic macular edema (DME), with and w...
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Article
Open AccessNatural killer cells modified with a Gpc3 aptamer enhance adoptive immunotherapy for hepatocellular carcinoma
Natural killer cells can attack cancer cells without prior sensitization, but their clinical benefit is limited owing to their poor selectivity that is caused by the lack of specific receptors to target tumor ...
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Article
Open AccessLncRNA TIALD contributes to hepatocellular carcinoma metastasis via inducing AURKA lysosomal degradation
The N6-methyladenosine (m6A) RNA methyltransferase METTL16 is an emerging player in RNA modification landscape and responsible for the deposition of m6A in a few transcripts. AURKA (aurora kinase A) has been c...
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Article
Open AccessNavoximod modulates local HSV-1 replication to reshape tumor immune microenvironment for enhanced immunotherapy via an injectable hydrogel
Oncolytic virotherapy can lead to tumor lysis and systemic anti-tumor immunity, but the therapeutic potential in humans is limited due to the impaired virus replication and the insufficient ability to overcome...
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Chapter and Conference Paper
An Optimal Maintenance Cycle Decision of Relay Protection Device Based on Weibull Distribution Model
of the problem that there is no accurate optimal maintenance cycle for relay protection device, this paper is based on the Weibull distribution model. We firstly analyze the maintenance cycle data, assume...
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Article
ZBP1 mediates interferon-induced necroptosis
Interferons (IFNs) play an important role in immunomodulatory and antiviral functions. IFN-induced necroptosis has been reported in cells deficient in receptor-interacting protein kinase 1 (RIPK1), Fas-associa...
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Article
HBV life cycle is restricted in mouse hepatocytes expressing human NTCP
Recent studies have revealed that human sodium taurocholate cotransporting polypeptide (SLC10A1 or NTCP) is a functional cellular receptor for hepatitis B virus (HBV). However, whether human NTCP can support H...
