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  1. Article

    Open Access

    Distinct promoter methylation profile reveals spatial epigenetic heterogeneity in 2 myeloma patients with multifocal extramedullary relapses

    Spatial and subclonal genetic heterogeneity in multiple myeloma (MM) have been demonstrated by sequencing of plasma cells from multi-focal regions, but studies of spatial epigenetic heterogeneity are scanty. H...

    Qiumei Yao, Gareth J. Morgan, Chor Sang Chim in Clinical Epigenetics (2018)

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  2. Article

    Open Access

    Frequent functional activation of RAS signalling not explained by RAS/RAF mutations in relapsed/refractory multiple myeloma

    RAS mutations are frequent in relapsed/refractory multiple myeloma (RRMM) but functional study in primary samples is scanty. Herein, in primary myeloma plasma cells of 17 suspected RRMM, functional activation of ...

    Kwan Yeung Wong, Qiumei Yao, Ling-Qing Yuan, Zhenhai Li… in Scientific Reports (2018)

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  3. Article

    Open Access

    VSTM-v1, a potential myeloid differentiation antigen that is downregulated in bone marrow cells from myeloid leukemia patients

    Leukocyte differentiation antigens often represent important markers for the diagnosis, classification, prognosis, and therapeutic targeting of myeloid leukemia. Herein, we report a potential leukocyte differe...

    Min **e, Ting Li, Ning Li, **lan Li, Qiumei Yao… in Journal of Hematology & Oncology (2015)

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