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  1. Article

    The effect of inhibition of endoplasmic reticulum stress on lipolysis in white adipose tissue in a rat model of chronic kidney disease

    Lipolysis in fat tissue plays an important role in the development of metabolic disturbances, a characteristic feature of chronic kidney disease (CKD). In the present study, we tested the hypothesis that the i...

    Yan Zhu, Yu-ling Chen, Cong Li, **ao-yan Ding, Guo-yu Xu in Acta Pharmacologica Sinica (2014)

  2. Article

    VEGF ameliorates tubulointerstitial fibrosis in unilateral ureteral obstruction mice via inhibition of epithelial-mesenchymal transition

    Vascular endothelial growth factor (VEGF) has been shown to be a survival factor for renal tubular epithelial cells. In the present study, we investigated whether administration of VEGF ameliorates tubulointer...

    Yao-guo Lian, Qiu-gen Zhou, Ying-juan Zhang, Fa-lei Zheng in Acta Pharmacologica Sinica (2011)

  3. Article

    Inhibition of tubulointerstitial fibrosis by pentoxifylline is associated with improvement of vascular endothelial growth factor expression

    Recent information indicates that pentoxifylline (PTX) has the ability to suppress inflammation and profibrotic cell proliferation. In this study, we investigated the effect of PTX on tubulointerstitial fibros...

    Qiu-gen Zhou, Fa-lei Zheng, Fan-fan Hou in Acta Pharmacologica Sinica (2009)