96 Result(s)
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Open AccessStudy on the ability of indoor plants to absorb and purify benzene pollution
The ability of indoor plants to purify benzene pollution is the basic basis for the selection of plants for ecological remediation of indoor benzene pollution. In this study, the purification rate and the puri...
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Targetable leukaemia dependency on noncanonical PI3Kγ signalling
Phosphoinositide-3-kinase-γ (PI3Kγ) is implicated as a target to repolarize tumour-associated macrophages and promote antitumour immune responses in solid cancers1–4. However, cancer cell-intrinsic roles of PI3Kγ...
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Open AccessArtificial intelligence enables precision diagnosis of cervical cytology grades and cervical cancer
Cervical cancer is a significant global health issue, its prevalence and prognosis highlighting the importance of early screening for effective prevention. This research aimed to create and validate an artific...
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Open AccessRecruitment of plasma cells from IL-21-dependent and IL-21-independent immune reactions to the bone marrow
Bone marrow plasma cells (BMPC) are the correlate of humoral immunity, consistently releasing antibodies into the bloodstream. It remains unclear if BMPC reflect different activation environments or maturation...
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Open AccessDynamic characteristics and evolution laws of underground brine in Mahai salt lake of Qaidam Basin during mining process
In the late stage of underground brine mining in salt lakes, the method of injecting fresh water is often used to extract the salt from the brine storage medium. This method of freshwater displacement breaks t...
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Open Access17 variants interaction of Wnt/β-catenin pathway associated with development of osteonecrosis of femoral head in Chinese Han population
The genes of Wnt/β-catenin pathway may have potential roles in fat accumulation of Non-traumatic osteonecrosis of the femoral head (ONFH), but the effects of their variants in the pathway on ONFH development h...
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Open AccessPublisher Correction: Pushing the thinness limit of silver films for flexible optoelectronic devices via ion-beam thinning-back process
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Open AccessPushing the thinness limit of silver films for flexible optoelectronic devices via ion-beam thinning-back process
Reducing the silver film to 10 nm theoretically allows higher transparency but in practice leads to degraded transparency and electrical conductivity because the ultrathin film tends to be discontinuous. Herei...
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Open AccessEfficacy of Bifidobacterium animalis subsp. lactis BL-99 in the treatment of functional dyspepsia: a randomized placebo-controlled clinical trial
Current treatment for functional dyspepsia (FD) has limited and unsustainable efficacy. Probiotics have the sustainable potential to alleviate FD. This randomized controlled clinical trial (Chinese Clinical Tr...
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Open AccessApproaching national climate targets in China considering the challenge of regional inequality
Achievement of national climate targets and the corresponding costs would entirely depend on regional actions within the country. However, because of substantial inequalities and heterogeneities among regions,...
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Open AccessUnconventional polarization fatigue in van der Waals layered ferroelectric ionic conductor CuInP2S6
Recent progress in two-dimensional ferroelectrics greatly expands the versatility and tunability in van der Waals heterostructure based electronics. However, the switching endurance issue that widely plagues c...
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Open AccessAsymmetric conformations and lipid interactions shape the ATP-coupled cycle of a heterodimeric ABC transporter
Here we used cryo-electron microscopy (cryo-EM), double electron-electron resonance spectroscopy (DEER), and molecular dynamics (MD) simulations, to capture and characterize ATP- and substrate-bound inward-fac...
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Open AccessActinide-lanthanide single electron metal-metal bond formed in mixed-valence di-metallofullerenes
Understanding metal-metal bonding involving f-block elements has been a challenging goal in chemistry. Here we report a series of mixed-valence di-metallofullerenes, ThDy@C2n (2n = 72, 76, 78, and 80) and ThY@C2n
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Open AccessReducing risks of antibiotics to crop production requires land system intensification within thresholds
Land system intensification has substantially enhanced crop production; however, it has also created soil antibiotic pollution, undermining crop production. Here, we projected soil antibiotic pollution risks t...
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Open AccessUnexpected do** effects on phonon transport in quasi-one-dimensional van der Waals crystal TiS3 nanoribbons
Do** usually reduces lattice thermal conductivity because of enhanced phonon-impurity scattering. Here, we report unexpected do** effects on the lattice thermal conductivity of quasi-one-dimensional (quasi...
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Open AccessBiology-guided deep learning predicts prognosis and cancer immunotherapy response
Substantial progress has been made in using deep learning for cancer detection and diagnosis in medical images. Yet, there is limited success on prediction of treatment response and outcomes, which has importa...
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Open AccessPolyfluorinated crosslinker-based solid polymer electrolytes for long-cycling 4.5 V lithium metal batteries
Solid polymer electrolytes (SPEs), which are favorable to form intimate interfacial contacts with electrodes, are promising electrolyte of choice for long-cycling lithium metal batteries (LMBs). However, typic...
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Open AccessInhibition of lysyl oxidases synergizes with 5-azacytidine to restore erythropoiesis in myelodysplastic and myeloid malignancies
Limited response rates and frequent relapses during standard of care with hypomethylating agents in myelodysplastic neoplasms (MN) require urgent improvement of this treatment indication. Here, by combining 5-...
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Open AccessA charged diatomic triple-bonded U≡N species trapped in C82 fullerene cages
Actinide diatomic molecules are ideal models to study elusive actinide multiple bonds, but most of these diatomic molecules have so far only been studied in solid inert gas matrices. Herein, we report a charge...
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Open AccessDirect production of olefins from syngas with ultrahigh carbon efficiency
Syngas conversion serves as a competitive strategy to produce olefins chemicals from nonpetroleum resources. However, the goal to achieve desirable olefins selectivity with limited undesired C1 by-products rem...
