190 Result(s)
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Article
Aspirin in Patients with Viral Hepatitis: Systematic Review and Meta-Analysis of Observational Studies
Hepatocellular carcinoma (HCC) is a disease demonstrating increasing morbidity and mortality, especially in patients with chronic viral hepatitis. Studies have shown that aspirin can reduce the incidence of li...
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Open AccessDisability level’s impact on blood pressure-mortality association in older long-term care adults: evidence from a large Chinese cohort study
Evidence of the optimal blood pressure (BP) target for older adults with disability in long-term care is limited. We aim to analyze the associations of BP with mortality in older adults in long-term care setti...
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Coactivation pattern analysis reveals altered whole-brain functional transient dynamics in autism spectrum disorder
Recent studies on autism spectrum disorder (ASD) have identified recurring states dominated by similar coactivation pattern (CAP) and revealed associations between dysfunction in seed-based large-scale brain n...
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Open AccessEpidemiological characteristics of neuroendocrine neoplasms in Bei**g: a population-based retrospective study
The incidence of neuroendocrine neoplasms (NENs) is rising rapidly worldwide. However, there are few reports on these heterogeneous diseases in China. Our study aimed to explore the epidemiological characteris...
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Open AccessEvaluation of optical coherence tomography angiography metrics in children and adolescents with type 1 diabetes: 4-year longitudinal study
To evaluate longitudinal changes in optical coherence tomography angiography (OCTA) metrics in children and adolescents with type 1 diabetes (T1D).
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Article
Progression rate of radiation-induced carotid stenosis in head and neck cancer survivors after statin treatment: a retrospective cohort study
Whether statin treatment is effective in retarding the progression of radiation-induced carotid stenosis (RICS) in head and neck cancer (HNC) survivors has not been well studied. The purpose of this study was ...
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Deep learning automatically assesses 2-µm laser-induced skin damage OCT images
The present study proposed a noninvasive, automated, in vivo assessment method based on optical coherence tomography (OCT) and deep learning techniques to qualitatively and quantitatively analyze the biologica...
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Open AccessThe efficacy of minimally invasive coronary artery bypass grafting (mics cabg) for patients with coronary artery diseases and diabetes: a single center retrospective study
conventional coronary artery bypass grafting (CCABG) tends to cause severe complications in patients with comorbid Coronary Artery Diseases (CAD) and diabetes. On the other hand, the Minimally Invasive Cardiac...
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ASO Author Reflections: Refining Radiotherapy Decisions in T3N0M0 Breast Cancer: A Nomogram-Based Approach
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Open AccessTreatment with the apoptosis inhibitor Asunercept reduces clone sizes in patients with lower risk Myelodysplastic Neoplasms
In low-risk Myelodysplastic Neoplasms (MDS), increased activity of apoptosis-promoting factors such as tumor necrosis factor (TNFα) and pro-apoptotic Fas ligand (CD95L) have been described as possible pathomec...
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Nomogram-Based Risk Stratification to Identify Patients with T3N0M0 Breast Cancer with Survival Benefit from Postmastectomy Radiotherapy
The survival benefit of postmastectomy radiotherapy (PMRT) for patients with T3N0M0 breast cancer remains controversial. This study aimed to identify patients with a survival benefit from PMRT by develo** a ...
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Open AccessEstablishing a Rat Model of Pelvic Organ Prolapse with All Compartment Defects by Persistent Cervical Tension
We hypothesized that applying cervical suction and persistent tension can develop a novel and efficient rat model of pelvic organ prolapse.
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Open AccessSynergistic suppression of ovarian cancer by combining NRF2 and GPX4 inhibitors: in vitro and in vivo evidence
Ovarian cancer is a significant challenge in women's health due to the lack of effective screening and diagnostic methods, often leading to late detection and the highest mortality rate among all gynecologic t...
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RUNX1-IT1 acts as a scaffold of STAT1 and NuRD complex to promote ROS-mediated NF-κB activation and ovarian cancer progression
Dysregulated expression of long-stranded non-coding RNAs is strongly associated with carcinogenesis. However, the precise mechanisms underlying their involvement in ovarian cancer pathogenesis remain poorly de...
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Open AccessEffectiveness of a socioecological model-guided, smart device-based, self-management-oriented lifestyle intervention in community residents: protocol for a cluster-randomized controlled trial
Healthy lifestyles are crucial for preventing chronic diseases. Nonetheless, approximately 90% of Chinese community residents regularly engage in at least one unhealthy lifestyle. Mobile smart devices-based he...
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Sun-Cross Running Suture Combined with Transverse to Longitudinal Skin Closure to Correct Severe Inverted Nipple
Inverted nipple deformity presents an unsatisfactory appearance that may induce an unpleasant sex life, but can also be associated with psychological discomfort and increased the functional problems, such as l...
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Open AccessA deep network DeepOpacityNet for detection of cataracts from color fundus photographs
Cataract diagnosis typically requires in-person evaluation by an ophthalmologist. However, color fundus photography (CFP) is widely performed outside ophthalmology clinics, which could be exploited to increase...
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Article
Gestational Gigantomastia: a Case Report
Gestational gigantomastia (GG) is a rare condition characterized by excessive breast enlargement during pregnancy. Reported incidence ranges from 1 in 28, 000 to 1 in 100, 000 pregnancies worldwide. The etiol...
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Article
Non-Surgical Therapeutic Strategies for Non-Melanoma Skin Cancers
Non-melanoma skin cancer (NMSC) is a globally prevalent skin disease, with basal cell carcinoma and squamous cell carcinoma accounting for 99% of NMSC cases. While surgical excision is the most common approach...
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Open AccessDeciphering tumor-infiltrating dendritic cells in the single-cell era
Dendritic cells (DCs) serve as a pivotal link connecting innate and adaptive immunity by processing tumor-derived antigens and activating T cells. The advent of single-cell sequencing has revolutionized the ca...
