Skip to main content

2 Result(s)

within Qingwei Chu Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter

and

  1. No Access

    Article

    Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP

    Biguanides such as metformin, which is the most widely prescribed drug for type-2 diabetes, are shown to antagonize the actions of glucagon by decreasing the levels of cyclic AMP.

    Russell A. Miller, Qingwei Chu, Jianxin **e, Marc Foretz, Benoit Viollet… in Nature (2013)

  2. No Access

    Article

    Hepatic insulin signalling is dispensable for suppression of glucose output by insulin in vivo

    Insulin signalling and nutrient levels coordinate the metabolic response to feeding in the liver. Insulin signals in hepatocytes to activate Akt, which inhibits Foxo1 suppressing hepatic glucose production (HG...

    Paul M. Titchenell, Qingwei Chu, Bobby R. Monks… in Nature Communications (2015)