-
Article
Open AccessThe association between osteoporosis and frailty: a cross-sectional observational study and mendelian randomization analysis
Osteoporosis and frailty are two common features in the elderly population. Despite many review articles mentioning the association between osteoporosis and frailty, there is a lack of original research direct...
-
Article
Open AccessIdentification of hub genes and diagnostic efficacy for triple-negative breast cancer through WGCNA and Mendelian randomization
Triple-negative breast cancer (TNBC) represents a particularly aggressive form of breast cancer with a poor prognosis due to a lack of targeted treatments resulting from limited a understanding of the underlyi...
-
Article
Open AccessReduced representative methylome profiling of cell-free DNA for breast cancer detection
Whole-genome methylation sequencing of cfDNA is not cost-effective for tumor detection. Here, we introduce reduced representative methylome profiling (RRMP), which employs restriction enzyme for depletion of A...
-
Article
Open AccessPredictors of surgery choices in women with early-stage breast cancer in China: a retrospective study
The breast-conserving surgery and reconstruction rate in China is relatively low when compared with those in Western countries. Moreover, predictors of surgical choices for women with breast cancer in China ha...
