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    Article

    A novel small-molecular CCR5 antagonist promotes neural repair after stroke

    Chemokine receptor 5 (CCR5) is one of the main co-receptors of HIV-1, and has been found to be a potential therapeutic target for stroke. Maraviroc is a classic CCR5 antagonist, which is undergoing clinical tr...

    Qing-lin Wu, Li-yuan Cui, Wen-yu Ma, Sha-sha Wang, Zhao Zhang in Acta Pharmacologica Sinica (2023)

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    Open Access

    A breakdown of metabolic reprogramming in microglia induced by CKLF1 exacerbates immune tolerance in ischemic stroke

    Ischemic stroke is characterized by the presence of reactive microglia. However, its precise involvement in stroke etiology is still unknown. We used metabolic profiling and showed that chemokine like factor 1...

    Wen-yu Ma, Qing-lin Wu, Sha-sha Wang, Hong-yun Wang in Journal of Neuroinflammation (2023)

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    Article

    The Role of AMPARs Composition and Trafficking in Synaptic Plasticity and Diseases

    AMPA receptors are tetrameric ionic glutamate receptors, which mediate 90% fast excitatory synaptic transmission induced by excitatory glutamate in the mammalian central nervous system through the activation o...

    Qing-Lin Wu, Yan Gao, Jun-Tong Li, Wen-Yu Ma in Cellular and Molecular Neurobiology (2022)

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    Article

    Research on the optimization mechanism of loading path in hydroforming process

    In this paper, the optimization mechanism of loading path in hydroforming process is researched. Firstly, the geometric model of an X-shaped tube is established by using 3D drawing software UG; the DYNAFORM so...

    Ying-ying Feng, Zong-an Luo, Hai-long Su in The International Journal of Advanced Manu… (2018)