-
Article
Targeting CXCL5 in Pancreatic Cancer Cells Inhibits Cancer Xenograft Growth by Reducing Proliferation and Inhibiting EMT Progression
Pancreatic cancer (PC) is the most lethal malignant tumor, with average survival period of about 10 months. C-X-C ligand 5 (CXCL5), an important chemokine for immune cell accumulation in tumor tissues, has bee...
-
Article
The relative strength of different floral visitors driving floral evolution within a Primula secundiflora population
Floral visitor assemblages within plant populations are usually composed of different visitors, and the relative abundance of these visitors also varies. Therefore, identifying the relative strength of these f...
-
Article
Open AccessCorrelation between the timing of autonomous selfing and floral traits: a comparative study from three selfing Gentianopsis species (Gentianaceae)
About 20% of angiosperms employ self-fertilization as their main mating strategy. In this study, we aimed to examine how the selfing timing correlated with floral traits in three Gentianopsis species in which aut...
-
Article
Similar behavior, different mechanisms: the research of the style bending of Alpinia species
The styles of the plants of genus Alpinia show a similar bending behavior. Each species has two types—hyper-type and cata-type. The styles of hyper-type bend downward first, and then bend upward second. The style...
-
Article
Protective effects of phillyrin against influenza A virus in vivo
Influenza A virus infection represents a great threat to public health. However, owing to side effects and the emergence of resistant virus strains, the use of currently available anti-influenza drugs may be l...
-
Article
Open AccessTail-like anther crest aids pollination by manipulating pollinator’s behaviour in a wild ginger
Innovative floral organs are widely distributed taxonomically in angiosperms and some of them are conspicuous and curious in morphology. Floral organs have long been supposed to play a crucial role in fertiliz...
-
Article
Open AccessExact solutions and multi-symplectic structure of the generalized KdV-type equation
The homogeneous balance of undetermined coefficients method is proposed to obtain not only exact solutions but also multi-symplectic structure of some nonlinear partial differential equations. Bilinear equation,
-
Article
Open AccessAsymmetrical disassortative pollination in a distylous primrose: the complementary roles of bumblebee nectar robbers and syrphid flies
Heterostyly is a floral polymorphism characterized by reciprocal herkogamy maintained through high levels of mating between morphs, serviced by appropriate pollinators. We studied how differential efficiency a...
-
Article
Phenotypic selection on the staminal lever mechanism in Salvia digitaloides (Labiaceae)
The staminal lever mechanism of pollination in Salvia has been considered as a key innovation, which was proposed to contribute to adaptive radiation of the genus. Considering its sophisticated interaction with p...
-
Article
The Down-Regulation of Notch1 Inhibits the Invasion and Migration of Hepatocellular Carcinoma Cells by Inactivating the Cyclooxygenase-2/Snail/E-cadherin Pathway In Vitro
The Notch signaling pathway plays an important role in cancer, but the mechanism by which Notch1 participates in invasion and migration of hepatocellular carcinoma (HCC) cells is unclear.
-
Article
Associations between high levels of Notch1 expression and high invasion and poor overall survival in hepatocellular carcinoma
Although Notch1 expression has been associated with progression or prognosis in various tumors, the role of Notch1 in hepatocellular carcinoma (HCC) remains unknown. This study sought to investigate the clinic...
-
Article
MicroRNA-10b promotes migration and invasion through CADM1 in human hepatocellular carcinoma cells
MicroRNA-10b (miR-10b) was recently reported to be dysregulated in some types of cancer and to play a role in invasion and metastasis. However, effects and potential mechanisms of action of miR-10b in the meta...
-
Article
Effects of indole-3-acetic acid and auxin transport inhibitors on the style curvature of three Alpinia species (Zingiberaceae)
The effects of indole-3-acetic acid (IAA) and the auxin transport inhibitors 2, 3, 5-triiodobenzoic acid (TIBA) and 1-N-naphthylphthalamic acid (NPA) on the style curvature of Alpinia platychilus,...
-
Article
Morphological and molecular evidence for natural hybridization in sympatric population of Roscoea humeana and R. cautleoides (Zingiberaceae)
The sympatric occurrence of some species in Roscoea is very common, but little information is available on natural hybridization. However, some intermediate individuals were found on the sympatric population of R...
-
Article
Subcellular localization of calcium during Alpinia mutica Roxb. (Zingiberaceae) style movement
The subcellular localization of calcium in Alpinia mutica Roxb. during style movement was studied in two morphs. In the styles, Ca-antimonate precipitates (ppts) were principally located in apoplasts, with some m...
-
Article
Effects of light and low temperature on the reciprocal style curvature of Flexistylous Alpinia Species (Zingiberaceae)
The style curvature (flexistyly) of Alpinia species in ginger family is a unique plant organ movement because the style of each flower curves twice during its 1-day anthesis and styles of two phenotypes of each A...
-
Article
Inflorescence and flower development in the Hedychieae (Zingiberaceae): Hedychium coccineum Smith
The inflorescence of Hedychium coccineum Smith is thyrse, and the primary bracts are initiated in a spiral phyllotactic pattern on the sides of the inflorescence dome. Cincinnus primordia are initiated on the fla...
-
Article
Fluorocitrate, an Inhibitor of Glial Metabolism, Inhibits the Up-Regulation of NOS Expression, Activity and NO Production in the Spinal Cord Induced by Formalin Test in Rats
Previous experiments have suggested that nitric oxide plays an important role in nociceptive transmission in the spinal cord. In order to explore the involvement of glia in the NO-mediated nociceptive transmis...
-
Article
The Role of Nitric Oxide in the Neuroprotection of Limb Ischemic Preconditioning in Rats
Brief limb ischemia was reported to protect neurons against injury induced by subsequent cerebral ischemia-reperfusion, and this phenomenon is known as limb ischemic preconditioning (LIP). To explore the role ...
-
Article
Nitric Oxide Participates in the Induction of Brain Ischemic Tolerance via Activating ERK1/2 Signaling Pathways
The present study was undertaken to observe in vivo changes of expression and phosphorylation of ERK1/2 proteins during brain ischemic preconditioning and effects of inhibiting generation of nitric oxide (NO) ...
