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Article
Open AccessThe survival prediction of advanced colorectal cancer received neoadjuvant therapy—a study of SEER database
The aim of study was to screen factors associated with the overall survival of colorectal cancer patients with lymph nodes metastasis who received neoadjuvant therapy and construct a nomogram model.
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Article
Open AccessEfficacy of different doses of corticosteroids in treating severe COVID-19 pneumonia
To investigate the efficacy of different doses of corticosteroids in treating severe coronavirus disease 2019 (COVID-19) pneumonia.
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Article
Open AccessMIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
The enrichment of peri-cancerous adipose tissue is a distinctive feature of colorectal cancer (CRC), accelerating disease progression and worsening prognosis. The communication between tumor cells and adjacent...
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Article
Open AccessEpidemiology of Asymptomatic Pre-heart Failure: a Systematic Review
To quantify the prevalence of asymptomatic pre-heart failure (pre-HF), progression to more severe stages, and associated mortality.
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Article
Short-Term and Quality of Life Outcomes of Patients Using Linear or Circular Stapling in Esophagojejunostomy after Laparoscopic Total Gastrectomy
Studies comparing the incidence of reflux esophagitis (RE) and patients’ quality of life (QoL) when using circular stapler (CS) and linear stapler (LS) in esophagojejunostomy (EJS) after laparoscopic total gas...
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Article
Open AccessAnesthesia management of atrial myxoma resection with multiple cerebral aneurysms: a case report and review of the literature
Embolic stroke is a common complication of atrial myxoma, whereas multiple cerebral aneurysms associated with atrial myxoma is rare. The pathogenesis of the cerebral vascular disease related to an atrial myxom...
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Article
Open AccessCytoplasmic SIRT1 inhibits cell migration and invasion by impeding epithelial–mesenchymal transition in ovarian carcinoma
Sirtuin1 (SIRT1) is a mammalian NAD+-dependent type III deacetylase that plays paramount roles in diverse cellular processes. The nucleocytoplasmic shuttling of SIRT1 was discovered more than a decade ago, but th...
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Article
Open AccessHypoxia promotes colorectal cancer cell migration and invasion in a SIRT1-dependent manner
Hypoxic microenvironments play a significant role in the progression of colorectal cancer (CRC). Silencing information regulator 1 (SIRT1), a class III histone deacetylase, modulates the multiple biological be...
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Article
In-situ construction of 2D direct Z-scheme g-C3N4/g-C3N4 homojunction with high photocatalytic activity
Constructing all-solid-state Z-scheme junction is a very effective strategy to design highly active photocatalysts for solar energy conversion and environmental purification. We herein firstly construct 2D g-C3N4
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Article
Open AccessSex differences in outcomes and associated factors among stroke patients with small artery occlusion in China
Sex differences in outcomes after small artery occlusion (SAO) stroke have not been well described, particularly in a Chinese population. We aimed to assess sex differences in outcomes and related risk factors...
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Article
Open AccessTriglycerides and total cholesterol concentrations in association with IFG/IGT in Chinese adults in Qingdao, China
To investigative the association of triglycerides (TG) and total cholesterol (TC) concentrations with impaired fasting glucose/ impaired glucose tolerance (IFG/IGT) in Chinese adults.
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Article
Open AccessGlucose Control and Weight Change Associated with Treatment with Exenatide Compared with Basal Insulin: A Retrospective Study
The aim of the study was to compare glycemic and weight change outcomes for type 2 diabetes patients treated with either exenatide once-weekly (EQW) or exenatide twice-daily (EBID) with those patients treated ...
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Article
Open AccessTolerability and Effectiveness of Exenatide Once Weekly Relative to Basal Insulin Among Type 2 Diabetes Patients of Different Races in Routine Care
Analyses of efficacy and tolerability of pharmacologic interventions are based on clinical trials that often include predominately white populations, in part because of challenges associated with recruitment a...
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Article
Relationships between tree-ring cell features of Pinus koraiensis and climate factors in the Changbai Mountains, Northeastern China
Anatomical characteristics have been proven useful for extracting climatic signals. To examine the climatic signals recorded by tree-ring cell features in the Changbai Mountains, we measured cell number and ce...
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Article
Open AccessGenetic polymorphisms in circadian negative feedback regulation genes predict overall survival and response to chemotherapy in gastric cancer patients
Circadian negative feedback loop (CNFL) genes play important roles in cancer development and progression. To evaluate the effects of single nucleotide polymorphisms (SNPs) in CNFL genes on the survival of GC p...
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Article
Imbalance in inpatient costs between urban and rural diabetes patients in **an, China
This study was to describe and compare the expenditures per hospital admission between urban and rural patients with a primary diagnosis of type 2 diabetes with and without complications in an urban tertiary h...
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Article
Open AccessImpact of a diabetes screening program on a rural Chinese population: a 3-year follow-up study
Screening for type 2 diabetes helps detect previously unknown diabetes and identify people with pre-diabetes, but the adverse impact of such screening on individuals labelled as pre-diabetes or classified as n...
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Article
Open AccessObesity attenuates gender differences in cardiovascular mortality
To estimate cardiovascular disease (CVD) mortality in relation to obesity and gender.
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Article
IL-17 gene polymorphism is associated with susceptibility to gastric cancer
We conducted a case–control study to investigate the role of three common IL-17A and IL-17F single nucleotide polymorphisms (SNPs) on the susceptibility to gastric cancer. A case–control study was conducted us...
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Article
The impact of new screen-detected and previously known type 2 diabetes on health-related quality of life: a population-based study in Qingdao, China
To examine and compare health-related quality of life (HRQoL) in people with previously known diabetes, new screen-detected asymptomatic diabetes and people without diabetes.
