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  1. Article

    Open Access

    Enhanced recombination empowers the detection and map** of Quantitative Trait Loci

    Modern plant breeding, such as genomic selection and gene editing, is based on the knowledge of the genetic architecture of desired traits. Quantitative trait loci (QTL) analysis, which combines high throughpu...

    Laia Capilla-Pérez, Victor Solier, Elodie Gilbault, Qichao Lian in Communications Biology (2024)

  2. Article

    Open Access

    A pan-genome of 69 Arabidopsis thaliana accessions reveals a conserved genome structure throughout the global species range

    Although originally primarily a system for functional biology, Arabidopsis thaliana has, owing to its broad geographical distribution and adaptation to diverse environments, developed into a powerful model in pop...

    Qichao Lian, Bruno Huettel, Birgit Walkemeier, Baptiste Mayjonade in Nature Genetics (2024)

  3. Article

    Open Access

    Structural variation and DNA methylation shape the centromere-proximal meiotic crossover landscape in Arabidopsis

    Centromeres load kinetochore complexes onto chromosomes, which mediate spindle attachment and allow segregation during cell division. Although centromeres perform a conserved cellular function, their underlyin...

    Joiselle B. Fernandes, Matthew Naish, Qichao Lian, Robin Burns in Genome Biology (2024)

  4. No Access

    Article

    SCEP1 and SCEP2 are two new components of the synaptonemal complex central element

    The synaptonemal complex (SC) is a proteinaceous structure that forms between homologous chromosomes during meiosis prophase. The SC is widely conserved across species, but its structure and roles during meiot...

    Nathalie Vrielynck, Marion Peuch, Stéphanie Durand, Qichao Lian in Nature Plants (2023)

  5. Article

    Open Access

    High-frequency synthetic apomixis in hybrid rice

    Introducing asexual reproduction through seeds – apomixis – into crop species could revolutionize agriculture by allowing F1 hybrids with enhanced yield and stability to be clonally propagated. Engineering syn...

    Aurore Vernet, Donaldo Meynard, Qichao Lian, Delphine Mieulet in Nature Communications (2022)

  6. Article

    Open Access

    Joint control of meiotic crossover patterning by the synaptonemal complex and HEI10 dosage

    Meiotic crossovers are limited in number and are prevented from occurring close to each other by crossover interference. In many species, crossover number is subject to sexual dimorphism, and a lower crossover...

    Stéphanie Durand, Qichao Lian, Juli **g, Marcel Ernst in Nature Communications (2022)

  7. Article

    Open Access

    The megabase-scale crossover landscape is largely independent of sequence divergence

    Meiotic recombination frequency varies along chromosomes and strongly correlates with sequence divergence. However, the causal relationship between recombination landscapes and polymorphisms is unclear. Here, ...

    Qichao Lian, Victor Solier, Birgit Walkemeier, Stéphanie Durand in Nature Communications (2022)

  8. No Access

    Article

    Modulation of evening complex activity enables north-to-south adaptation of soybean

    Soybean, a typical short-day crop, is sensitive to photoperiod, which is a major limiting factor defining its north-to-south cultivation range. The long-juvenile (LJ) trait is controlled primarily by the J locus ...

    **aolong Fang, Yapeng Han, Mengshi Liu, Jiacan Jiang in Science China Life Sciences (2021)

  9. Article

    Open Access

    New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage

    Poly (ADP-ribosyl) ation (PARylation) is an important posttranslational modification that regulates DNA repair, gene transcription, stress responses and developmental processes in multicellular organisms. Poly...

    Zongying Gu, Weiyang Pan, Wei Chen, Qichao Lian, Qiao Wu, Zeyu Lv in BMC Plant Biology (2019)