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Article
Naphthylisoquinoline alkaloids, a new structural template inhibitor of Nav1.7 sodium channel
Voltage-gated sodium channel 1.7 (Nav1.7) remains one of the most promising drug targets for pain relief. In the current study, we conducted a high-throughput screening of natural products in our in-house comp...
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Article
Open AccessGMMAD: a comprehensive database of human gut microbial metabolite associations with diseases
The natural products, metabolites, of gut microbes are crucial effect factors on diseases. Comprehensive identification and annotation of relationships among disease, metabolites, and microbes can provide effi...
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Article
Glucagon-Like Peptide 1 Receptor Agonists in Alzheimer’s Disease
Glucagon-like peptide-1 receptor agonist (GLP-1RA)has been found to have a complex and extensive connection with Alzheimer’s disease (AD). The study is to further determine the therapeutic effect of GLP-1RA on...