6 Result(s)

Article

Adenine base editor corrected ADPKD point mutations in hiPSCs and kidney organoids

Autosomal dominant polycystic kidney disease (ADPKD) is a dominant genetic disorder caused primarily by mutations in the PKD1 gene, resulting in the formation of numerous cysts and eventually kidney failure. Howe...

**gwen Wang, Yanling Qiu, Lei Zhang, **nyao Zhou, Sihui Hu… in Advanced Biotechnology (2024)

Article

Transition metal-free visible light photoredox-catalyzed remote C(sp³)−H borylation enabled by 1,5-hydrogen atom transfer

The borylation of unreactive carbon-hydrogen bonds is a valuable method for transforming feedstock chemicals into versatile building blocks. Here, we describe a transition metal-free method for the photoredox-...

Beiqi Sun, Wenke Li, Qianyi Liu, Gaoge Zhang, Fanyang Mo in Communications Chemistry (2023)

Article

Prediction of high-speed train delay propagation based on causal text information

The delay-causing text data contain valuable information such as the specific reasons for the delay, location and time of the disturbance, which can provide an efficient support for the prediction of train del...

Qianyi Liu, Shengjie Wang, Zhongcan Li, Li Li, Jun Zhang… in Railway Engineering Science (2023)

Article

Shining Light on Anion-Mixed Nanocatalysts for Efficient Water Electrolysis: Fundamentals, Progress, and Perspectives

Article

Mycobacterium tuberculosis Heat-Shock Protein 16.3 Induces Macrophage M2 Polarization Through CCRL2/CX3CR1

Mycobacterium tuberculosis, the pathogen of tuberculosis (TB), can survive in host macrophages and induce macrophages to M2 phenotype might result in latent MTB infection. During the latent phase, the expression ...

Yanhao Zhang, Shanshan Li, Qianyi Liu, Ruiying Long, Jihong Feng, Huan Qin… in Inflammation (2020)

Article

Gab2 facilitates epithelial-to-mesenchymal transition via the MEK/ERK/MMP signaling in colorectal cancer

Grb2-associated binder 2 (Gab2), a scaffolding adaptor protein, has recently been implicated in cancer progression. However, the role of Gab2 in the progression and metastasis of colorectal cancer (CRC) remain...

Chenbo Ding, Junmin Luo, Longmei Li… in Journal of Experimental & Clinical Cancer … (2016)