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  1. Article

    Open Access

    E3 ubiquitin ligase on the biological properties of hematopoietic stem cell

    Hematopoietic stem cells are a group of heterogeneity cells with the potential to differentiate into various types of mature blood cells. Their basic biological properties include quiescence, self-renewal, mul...

    Qianru Zhan, **g Wang, Heyang Zhang, Lijun Zhang in Journal of Molecular Medicine (2023)

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  2. Article

    Open Access

    TLS/FUS-ERG fusion gene in acute leukemia and myelodysplastic syndrome evolved to acute leukemia: report of six cases and a literature review

    To investigate the pathogenesis and the refractory/relapse mechanisms in patients with t(16;21)(p11;q22), we retrospectively analyzed the clinical data of six cases in our hospital and sixty-two cases reported...

    Heyang Zhang, Qianru Zhan, **aoxue Wang, Feng Gao, **xiang Yu… in Annals of Hematology (2022)

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  3. Article

    Open Access

    The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia

    Acute lymphoblastic leukemia (ALL) has been a huge threat for people's health and finding effective target therapy is urgent and important. WWP2, as one of E3 ubiquitin ligase, is involved in many biological p...

    **nxin Lu, **nyue Huang, Haiqi Xu, Saien Lu, Shilong You, Jiaqi Xu… in Cell Death Discovery (2022)

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