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Article
Open AccessMalassezia restricta as an unexpected cause of infectious osteomyelitis diagnosed by metagenomic sequencing: a case report and literature review
Malassezia restricta, a lipophilic and lipodependent yeast belonging to the basidiomycetes group, is an opportunistic fungal pathogen associated with various skin diseases, including seborrheic dermatitis and dan...
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Article
Open AccessDEPDC5 protects CD8+ T cells from ferroptosis by limiting mTORC1-mediated purine catabolism
Peripheral CD8+ T cell number is tightly controlled but the precise molecular mechanism regulating this process is still not fully understood. In this study, we found that epilepsy patients with loss of function ...
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Article
Open AccessAuthor Correction: Optogenetic-controlled immunotherapeutic designer cells for post-surgical cancer immunotherapy
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Article
Post-disaster spatial reconstruction from the perspective of a rural settlement niche in the upper reaches of the Minjiang River
Post-disaster recovery and reconstruction provide an effective way to reduce the disaster vulnerability of, and promote leapfrog development in, an affected area. To date, studies that have used administrative...
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Article
Brain Cognition Mechanism-Inspired Hierarchical Navigation Method for Mobile Robots
Autonomous navigation is a fundamental problem in robotics. Traditional methods generally build point cloud map or dense feature map in perceptual space; due to lack of cognition and memory formation mechanism...
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Article
Open AccessFOXP3+ regulatory T cell perturbation mediated by the IFNγ-STAT1-IFITM3 feedback loop is essential for anti-tumor immunity
Targeting tumor-infiltrating regulatory T cells (Tregs) is an efficient way to evoke an anti-tumor immune response. However, how Tregs maintain their fragility and stability remains largely unknown. IFITM3 and...
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Chapter and Conference Paper
An Enhanced Adaptive Shuffled Complex Evolution Algorithm for Hydrological Model Parameter Calibration
An enhanced adaptive shuffled complex evolution algorithm (EASCE) is presented for model parameter calibration in this paper. This proposed algorithm is built based on the shuffled complex evolution algorithm ...
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Article
WCDForest: a weighted cascade deep forest model toward the classification tasks
The deep forest model, a random forest (RF) ensemble approach and an alternative to Deep Neural Network (DNN), has performance highly competitive to DNN in many classification tasks. However, deep forest model...
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Article
Open AccessVisualizing symmetry-breaking electronic orders in epitaxial Kagome magnet FeSn films
Kagome lattice hosts a plethora of quantum states arising from the interplay of topology, spin-orbit coupling, and electron correlations. Here, we report symmetry-breaking electronic orders tunable by an appli...
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Article
Open AccessApplication of a modified tetra-primer ARMS–PCR assay for rapid Panax species identity authentication in ginseng products
Panax ginseng products can be adulterated with materials from other Panax species. The purpose of this study is to provide a rapid P. ginseng authentication method for simultaneous identification of P. ginseng an...
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Article
The composition and roles of gastric stem cells in epithelial homeostasis, regeneration, and tumorigenesis
The epithelial lining of the stomach undergoes rapid turnover to preserve its structural and functional integrity, a process driven by long-lived stem cells residing in the antral and corpus glands. Several su...
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Article
Open AccessRisk Assessment of Debris Flows Along the Karakoram Highway (Kashgar-Khunjerab Section) in the Context of Climate Change
The Karakoram highway (KKH) is renowned for its complex natural environment and geological conditions. The climate changes drastically and directly influences the frequency and magnitude of debris flows in thi...
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Article
Open AccessEstimation of Shallow Landslide Susceptibility Incorporating the Impacts of Vegetation on Slope Stability
This study aimed to develop a physical-based approach for predicting the spatial likelihood of shallow landslides at the regional scale in a transition zone with extreme topography. Shallow landslide susceptib...
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Article
Assessment of heavy metal pollution in Laizhou Bay (China) using the ecological risk index and the integrated biomarker response of the goby Acanthogobius ommaturus
We used the Integrated Biological Responses version 2 (IBRv2) method to evaluate the biological effects of heavy metals in the sediments in Laizhou Bay, China on the benthic goby Acanthogobius ommaturus. In Decem...
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Article
Open AccessAmino acid metabolism in immune cells: essential regulators of the effector functions, and promising opportunities to enhance cancer immunotherapy
Amino acids are basic nutrients for immune cells during organ development, tissue homeostasis, and the immune response. Regarding metabolic reprogramming in the tumor microenvironment, dysregulation of amino a...
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Article
A Comparative Applied Study on Optimizing Printing Parameters for Six Fused Deposition Modeling Materials
The characteristics of six materials [acrylonitrile butadiene styrene (ABS), polylactic acid (PLA), thermoplastic polyurethane (TPU), polyvinyl alcohol (PVA), polyethylene terephthalate glycol (PETG), and poly...
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Article
E3 ubiquitin ligases in cancer stem cells: key regulators of cancer hallmarks and novel therapeutic opportunities
Human malignancies are composed of heterogeneous subpopulations of cancer cells with phenotypic and functional diversity. Among them, a unique subset of cancer stem cells (CSCs) has both the capacity for self-...
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Article
EAAE: A Generative Adversarial Mechanism Based Classfication Method for Small-scale Datasets
When used for small-scale datasets classification tasks, deep neural networks are difficult to train, which results in the network not extracting useful features and the low accuracy of network. This paper pro...
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Article
Human pose estimation with gated multi-scale feature fusion and spatial mutual information
Although human pose estimation has achieved great success, the ambiguity of joint prediction has not been well resolved, especially in complex situations (crowded scenes, occlusions, and unnormal poses). We th...
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Article
Consequences and Mechanisms of Left Atrium Remodeling in Aging Rabbits
To investigate the consequences and mechanisms of myocardium remodeling of aging left atrium, we analyzed the main cardiac electrophysiological parameters such as rest membrane potential, action potential ampl...
