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Article
Ferritin-mediated mitochondrial iron homeostasis is essential for the survival of hematopoietic stem cells and leukemic stem cells
Iron metabolism plays a crucial role in cell viability, but its relationship with adult stem cells and cancer stem cells is not fully understood. The ferritin complex, responsible for intracellular iron storag...
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Article
Concrete surface roughness measurement method based on edge detection
The strength of the bond between concretes is attributed to surface roughness. Therefore, it is necessary to quantify the roughness of concrete surfaces. In the traditional method, concrete surface roughness i...
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Article
Open AccessGBP2 is a prognostic biomarker and associated with immunotherapeutic responses in gastric cancer
The interferon-induced protein known as guanylate-binding protein 2 (GBP2) has been linked to multiple different cancer types as an oncogenic gene. Although the role of GBP2 in cancer has been preliminarily ex...
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Article
Silicon-mediated alleviation of cadmium toxicity in soil–plant system: historical review
The contamination of crops by Cd is a worldwide problem that needs to be addressed for minimizing risk for human health. Today, numerous investigations have demonstrated that Si plays a role in reducing Cd tox...
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Article
A deep learning-based model improves diagnosis of early gastric cancer under narrow band imaging endoscopy
Diagnosis of early gastric cancer (EGC) under narrow band imaging endoscopy (NBI) is dependent on expertise and skills. We aimed to elucidate whether artificial intelligence (AI) could diagnose EGC under NBI a...
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Article
Silicon-Calcium Synergetic Alleviation of Cadmium Toxicity in the Paddy Soil-Rice System: from Plot Experiment to Field Demonstration
Cadmium (Cd) contamination threatens the safety of rice and seriously endangers human health. In plot and field experiments, the effect of combined silicon (Si) and calcium (Ca) application on Cd toxicity and ...
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Article
Open AccessCircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA
Aberrant expression of circular RNAs (circRNAs) contributes to the initiation and progression of human malignancies, but the underlying mechanisms remain largely elusive.
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Article
Open AccessClinical significance and correlation of PD-L1, B7-H3, B7-H4, and TILs in pancreatic cancer
B7 molecules play significant roles in regulating tumor immunity, but their expression patterns and immuno-biological correlations in pancreatic cancer (PaCa) have not been fully discussed.
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Article
Open AccessCo-deficiency of B7-H3 and B7-H4 identifies high CD8 + T cell infiltration and better prognosis in pancreatic cancer
Immunotherapy is a novel hotspot for the treatment of pancreatic adenocarcinoma (PAAD). However, potential biomarkers which could identify the inflamed tumor microenvironment (TME) are urgently required.
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Article
The Kinematic Calibration of a Drilling Robot with Optimal Measurement Configurations Based on an Improved Multi-objective PSO Algorithm
In aircraft assembly, robot drilling system has been widely used to enhance the efficiency and quality of assembly holes' manufacturing. However, the industrial robot used by the drilling robot has low absolut...
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Article
Open AccessYWHAZ interacts with DAAM1 to promote cell migration in breast cancer
Dishevelled-associated activator of morphogenesis 1 (DAAM1) is a critical driver in facilitating metastasis in breast cancer (BrCa). However, molecular mechanisms for the regulation of DAAM1 activation are onl...
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Article
Long-term outcomes of endoscopic treatment for colorectal laterally spreading tumor: a large-scale multicenter retrospective study from China
Laterally spreading tumor (LST) is a type of precancerous lesion of colorectal cancer with high malignant potential. The present study aimed to evaluate long-term outcomes of endoscopic treatment for LST in Ch...
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Article
High expression of FABP4 in colorectal cancer and its clinical significance
To investigate the relationship between the fatty acid-binding protein 4 (FABP4) and colorectal cancer (CRC).
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Article
Regulation of As and Cd accumulation in rice by simultaneous application of lime or gypsum with Si-rich materials
Calcium (Ca) and silicon (Si) have been found to reduce inorganic pollutant accumulation by agricultural plants. Arsenic (As) and cadmium (Cd) are the most common and dangerous inorganic pollutants in cultivat...
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Article
Open AccessPrevalence of gastric cancer precursors in gastroscopy-screened adults by family history of gastric cancer and of cancers other than gastric
People are at a high risk of gastric cancer if their first-degree relatives suffered from atrophic gastritis (AG), intestinal metaplasia (IM), intraepithelial neoplasia (IEN), dysplasia (DYS), or gastric cance...
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Article
Design, Fabrication and Experiments of an Anthropomorphic Finger with Combined Compliant Joints
Fingers are the basic components of anthropomorphic hands. At present, most anthropomorphic fingers utilize rigid joints, which have obvious fabrication and assembly complexities as well as limited flexibility...
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Article
Open AccessProfiling circRNA and miRNA of radiation-induced esophageal injury in a rat model
Evidence has also shown that micro ribonucleic acid (miRNA) plays an important role in many cellular processes. However, it is unclear how ionizing radiation causes the miRNA and circular ribonucleic acid (cir...
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Article
Effect of Charge Density on Spray Characteristics, Combustion Process, and Emissions of Heavy-Duty Diesel Engines
In-cylinder charge density at top dead center is an important parameter of diesel engines and is influenced by intake pressure, intake temperature, and compression ratio. The effects of charge density on fuel ...
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Article
Effect of Heavy-Duty Diesel Engine Operating Parameters on Particle Number and Size Distribution at Low Speed Condition
Experiments and simulations were used to investigate the effect of a range of engine operating parameters and fuel characteristics on the particle size and particle number (PN) concentration at low speed and i...
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Article
Impacts of sewer deposits on the urban river sediment after rainy season and bioremediation of polluted sediment
Impacts of deposits discharged from a municipal pipe on urban river sediment were investigated in the Hucang River in Tian**, China. At the outlet of the pump station, the average concentrations of total nitr...
