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Article
Redifferentiation of genetically modified dedifferentiated chondrocytes in a microcavitary hydrogel
We genetically modified dedifferentiated chondrocytes (DCs) using lentiviral vectors and adenoviral vectors encoding TGF-β3 (referred to as transgenic groups below) and encapsulated these DCs in the microcavit...
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Chapter and Conference Paper
A Novel Threat Assessment Model Based on GIFSS for Multi-UAV Air Combat Under Uncertain Information
The existing multi-UAV cooperative air combat threat assessment models is inadequate to reflect the dynamic threat of the target, uncertain recognition result, and the threat to the whole formation. Aiming at ...
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Article
Open AccessEffect of postoperative application of esketamine on postoperative depression and postoperative analgesia in patients undergoing pancreatoduodenectomy: a randomized controlled trial protocol
Pancreatoduodenectomy (PD) is traumatic, difficult to perform, and has a high incidence of postoperative complications and perioperative mortality. Postoperative complications and pain occur frequently and ser...
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Article
Open AccessThe prediction of postoperative delirium with the preoperative bispectral index in older aged patients: a cohort study
Postoperative delirium (POD) is the most common postoperative complication in elderly patients, especially in older aged patients (aged 75 years or over). The development of electroencephalography analysis cou...
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Article
Fuzzy ELECTRE II Location Preselection Model of Temporary Marine Dum** Area Based on S-Shaped Utility Function and Combination Weight
As an important link of marine dum** management, reasonable selection of the location of temporary marine dum** areas is of great significance to the high-quality development of the marine economy. To solv...
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Article
An Extended PROMETHEE II Method for Multi-attribute Group Decision-Making Under q-Rung Orthopair 2-Tuple Linguistic Environment
The q-rung orthopair 2-tuple linguistic numbers (q-RO2TLNs) are helpful tools to represent fuzzy or indeterminate evaluation information. The classical PROMETHEE II is a flexible outranking method for complete...
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Article
Progress in Osteochondral Regeneration with Engineering Strategies
Osteoarthritis, the main cause of disability worldwide, involves not only cartilage injury but also subchondral bone injury, which brings challenges to clinical repair. Tissue engineering strategies provide a ...
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Article
An Extended QUALIFLEX Method with Comprehensive Weight for Green Supplier Selection in Normal q-Rung Orthopair Fuzzy Environment
Green supplier selection (GSS) plays an irreplaceable role in green supply chain management and environmental protection. Simultaneously, it is widely studied as a typical multi-attribute decision-making (MADM...
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Article
Genome-wide CRISPR activation screen identifies candidate receptors for SARS-CoV-2 entry
The outbreak of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has created a global health crisis. SARS-CoV-2 infects varieties of tissues where the known receptor ACE2 is low or almost absent, sugge...
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Article
Open AccessCross-Disorder Analysis of De Novo Mutations in Neuropsychiatric Disorders
The clinical similarity among different neuropsychiatric disorders (NPDs) suggested a shared genetic basis. We catalogued 23,109 coding de novo mutations (DNMs) from 6511 patients with autism spectrum disorder...
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Article
Effect of the surface microstructure of arsenopyrite on the attachment of Sulfobacillus thermosulfidooxidans in the presence of dissolved As(III)
Understanding bacterial adsorption and the evolution of biofilms on arsenopyrite with different surface structures is of great significance to clarifying the mechanism of microbe-mineral interfacial interactio...
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Article
Open AccessModular gateway-ness connectivity and structural core organization in maritime network science
Around 80% of global trade by volume is transported by sea, and thus the maritime transportation system is fundamental to the world economy. To better exploit new international ship** routes, we need to unde...
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Article
Open AccessMulti-omic analysis in transgenic mice implicates omega-6/omega-3 fatty acid imbalance as a risk factor for chronic disease
An unbalanced increase in dietary omega-6 (n-6) polyunsaturated fatty acids (PUFA) and decrease in omega-3 (n-3) PUFA in the Western diet coincides with the global rise in chronic diseases. Whether n-6 and n-3...
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Article
Two amino acids missing of MtrA resulted in increased erythromycin level and altered phenotypes in Saccharopolyspora erythraea
The MtrA-MtrB two-component regulatory system is highly conserved in Actinobacteria and plays crucial roles in cell cycle progression, cell morphology, antibiotic resistance, and osmoprotection. Previously, we re...
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Article
Open AccessInherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model
We previously performed targeted sequencing of autism risk genes in probands from the Autism Clinical and Genetic Resources in China (ACGC) (phase I). Here, we expand this analysis to a larger cohort of patien...
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Article
A Coupled Dynamic Model of Brand Acceptance and Promotive Information Spreading
When people try to decide to buy or not to, they are often influenced by both their inherent opinions and the social marketing activities e.g. advertising, social news with strong point of view. Then people wi...
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Article
Non-monotonic piezocone dissipation curves of backfills in a soil-bentonite slurry trench cutoff wall
Pore pressure dissipation during piezocone testing provides a unique tool for estimating the hydraulic properties of in-situ backfills in soil-bentonite (SB) slurry trench cutoff walls. Six tests were performe...
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Article
Evaluating water reuse applications under uncertainty: generalized intuitionistic fuzzy-based approach
Water reuse is a viable option to increase urban water supply, especially under new realities of climate change and increasing anthropogenic activities. A sustainable water reuse application should be cost-eff...
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Article
Open AccessEis, a novel family of arylalkylamine N-acetyltransferase (EC 2.3.1.87)
Enhanced intracellular survival (Eis) proteins were found to enhance the intracellular survival of mycobacteria in macrophages by acetylating aminoglycoside antibiotics to confer resistance to these antibiotic...
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Article
Cloning of the ANT gene and its expression profiles at different developmental stages and post-molting times in the ridgetail white prawn Exopalaemon carinicauda
To investigate the roles of the ANT gene, which codes for adenine nucleotide translocase (ANT) during crustacean development, a full-length cDNA sequence of EcANT in the ridgetail white prawn Exopalaemon carinica...
