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    Article

    The LIM protein AJUBA promotes colorectal cancer cell survival through suppression of JAK1/STAT1/IFIT2 network

    The LIM protein AJUBA is a scaffold protein participating in the regulation of cell adhesion, mitosis, DNA damage, cell differentiation, proliferation, migration and gene transcription. However, its roles in t...

    H Jia, L Song, Q Cong, J Wang, H Xu, Y Chu, Q Li, Y Zhang, X Zou, C Zhang in Oncogene (2017)

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    Article

    RN1, a novel galectin-3 inhibitor, inhibits pancreatic cancer cell growth in vitro and in vivo via blocking galectin-3 associated signaling pathways

    Galectin-3 (Gal-3) has been implicated in pancreatic ductal adenocarcinoma (PDAC), and its candidacy as a therapeutic target has been evaluated. Gal-3 is widely upregulated in tumors, and its expression is ass...

    L Zhang, P Wang, Y Qin, Q Cong, C Shao, Z Du, X Ni, P Li, K Ding in Oncogene (2017)

  3. Article

    Open Access

    Enhanced Iron and Zinc Accumulation in Genetically Engineered Wheat Plants Using Sickle Alfalfa (Medicago falcata L.) Ferritin Gene

    Iron deficiency is the most common nutritional disorder, affecting over 30% of the world’s human population. The primary method used to alleviate this problem is nutrient biofortification of crops so as to imp...

    D. J. Liu, Y. B. Wang, C. H. Guo, Q. Cong, X. Gong in Cereal Research Communications (2016)

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    Article

    p57Kip2 is an unrecognized DNA damage response effector molecule that functions in tumor suppression and chemoresistance

    The DNA damage response (DDR) helps to maintain genome integrity, suppress tumorigenesis and mediate the radiotherapeutic and chemotherapeutic effects on cancer. Here we report that p57Kip2, a cyclin-dependent...

    H Jia, Q Cong, J F L Chua, H Liu, X **a, X Zhang, J Lin, S L Habib, J Ao, Q Zuo in Oncogene (2015)