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Article
Open AccessPhenotypic and Genomic Analysis of Hypervirulent Human-associated Bordetella bronchiseptica
B. bronchiseptica infections are usually associated with wild or domesticated animals, but infrequently with humans. A recent phylogenetic analysis distinguished two distinct B. bronchiseptica subpopulations, des...
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Article
Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry
A hybrid linear ion-trap Fourier-transform ion cyclotron resonance mass spectrometer was used for top-down characterization of the abundant human salivary cystatins, including S, S1, S2, SA, SN, C, and D, usin...
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Article
Micro-heterogeneity of human saliva peptide P-C characterized by high-resolution top-down fourier-transform mass spectrometry
Top-down proteomics characterizes protein primary structures with unprejudiced descriptions of expressed and processed gene products. Gene sequence polymorphisms, protein post-translational modifications, and ...
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Article
A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells
The calcium-binding protein CRACR2A positively regulates the activity of CRAC channels. CRACR2A is a ternary complex which binds to, and stabilizes, the interaction between STIM1 and Orai1, and disassociates a...
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Article
The minimum information about a proteomics experiment (MIAPE)
Both the generation and the analysis of proteomics data are now widespread, and high-throughput approaches are commonplace. Protocols continue to increase in complexity as methods and technologies evolve and d...
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Chapter and Conference Paper
Effect of Aldosterone on Na+ Transport in a Model Renal Epithelial Cell Line
Aldosterone, a principle hormone controlling salt and water balance in vertebrates, acts by altering the expression of defined proteins in transporting epithelial cells. While several aldosterone-induced prote...
