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Article
Open AccessHigh-content image screening to identify chemical modulators for peroxisome and ferroptosis
The peroxisome is a dynamic organelle with variety in number, size, shape, and activity in different cell types and physiological states. Recent studies have implicated peroxisomal homeostasis in ferroptosis s...
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Article
The interplay of miRNAs and ferroptosis in diseases related to iron overload
Ferroptosis has been conceptualized as a novel cell death modality distinct from apoptosis, necroptosis, pyroptosis and autophagic cell death. The sensitivity of cellular ferroptosis is regulated at multiple l...
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Protocol
Determining Macrophage Polarization upon Metabolic Perturbation
Metabolic reprograming controlling macrophage activation and function is emerging as new regulatory circuit on sha** immune responses. Generally, lipopolysaccharides (LPS)-induced pro-inflammatory activated ...