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  1. No Access

    Article

    DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway

    Recurrent breast cancer presents significant challenges with aggressive phenotypes and treatment resistance. Therefore, novel therapeutics are urgently needed. Here, we report that murine recurrent breast tumo...

    Chao-Chieh Lin, Wen-Hsuan Yang, Yi-Tzu Lin, **aohu Tang, Po-Han Chen in Oncogene (2021)

  2. Article

    Open Access

    Duodenal major papilla morphology can affect biliary cannulation and complications during ERCP, an observational study

    We investigated whether duodenal major papilla morphology could be a risk factor for failure of selective biliary cannulation (SBC) and post endoscopic retrograde cholangiography and pancreatography (ERCP) com...

    Po-Han Chen, Chun-Fang Tung, Yen-Chung Peng, Hong-Zen Yeh in BMC Gastroenterology (2020)

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    Article

    Efficiency of quantitative echogenicity for investigating supraspinatus tendinopathy by the gray-level histogram of two ultrasound devices

    The gray-level histogram of ultrasound is a promising tool for scanning the hypoechogenic appearance of supraspinatus tendinopathy, and the aim of this study was to test the hypothesis that the gray-level valu...

    Jiun-Cheng Hsu, Po-Han Chen, Kuo-Chin Huang in Journal of Medical Ultrasonics (2017)

  4. No Access

    Article

    Discovery, Genomic Analysis, and Functional Role of the Erythrocyte RNAs

    Human erythrocytes are responsible for oxygen delivery in the body. Erythrocytes are a product of terminal differentiated erythroid cells that accumulate hemoglobin and exclude nuclei. The long-held convention...

    Po-Han Chen, Jonathan Hong, Jen-Tsan Chi in Current Pathobiology Reports (2017)

  5. Article

    Open Access

    Early detection of unhealthy behaviors, the prevalence and receipt of antiviral treatment for disabled adult hepatitis B and C carriers

    Evidence indicates that hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are the leading causes of liver cirrhosis and hepatocellular carcinoma. Antiviral treatments have recently been reported a...

    Sui-Whi Jane, Ming-Shyan Lin, Wen-Nan Chiu, Li-Ju Lai, Po-Han Chen in BMC Public Health (2016)

  6. Article

    Open Access

    Benefits of biphasic calcium phosphate hybrid scaffold-driven osteogenic differentiation of mesenchymal stem cells through upregulated leptin receptor expression

    The use of mesenchymal stem cells (MSCs) and coralline hydroxyapatite (HA) or biphasic calcium phosphate (BCP) as a bone substitute for posterolateral spinal fusion has been reported. However, the genes and mo...

    Chi-Chien Niu, Song-Shu Lin, Wen-Jer Chen in Journal of Orthopaedic Surgery and Research (2015)

  7. No Access

    Article

    Decreased Total MKP-1 Protein Levels Predict Poor Prognosis in Breast Cancer

    MKP-1 dephosphorylates and inactivates MAPKs, whose constitutive activations have been associated with human cancers.

    Ming-Feng Hou, Chien-Wei Chang, Fang-Ming Chen, Shen-Nien Wang in World Journal of Surgery (2012)