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Open AccessCorpus callosum in children with neurodevelopmental delay: MRI standard qualitative assessment versus automatic quantitative analysis
The corpus callosum (CC) is a key brain structure. In children with neurodevelopmental delay, we compared standard qualitative radiological assessments with an automatic quantitative tool.
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When Hypnosis Becomes a “First-Line” Teaching, the University Wins
Hypnosis is historically present in universities, with a variable representation according to the times. The challenge of this presence seems to be twofold: to promote and maintain a link between the teaching ...
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Article
Open AccessSHR/NCrl rats as a model of ADHD can be discriminated from controls based on their brain, blood, or urine metabolomes
Attention-Deficit Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorder characterized by inattention, impulsivity, and hyperactivity. The neurobiological mechanisms underlying ADH...
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Respiratory chain inhibition: one more feature to propose MPTP intoxication as a Leigh syndrome model
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxicated mice have been widely used to model the loss of dopaminergic neurons. As this treatment leads to basal ganglia degeneration, it was proposed that...
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Article
Proton MR spectroscopic imaging of basal ganglia and thalamus in neurofibromatosis type 1: correlation with T2 hyperintensities
Neurofibromatosis type 1 (NF1) is frequently associated with hyperintense lesions on T2-weighted images called “unidentified bright objects” (UBO). To better characterize the functional significance of UBO, we...
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Article
Open AccessRegional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport
The gibbon ape leukemia virus (GALV), the amphotropic murine leukemia virus (AMLV) and the human T-cell leukemia virus (HTLV) are retroviruses that specifically bind nutrient transporters with their envelope g...
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Open AccessCapture in the metabolic arena: co-selection of gamma and deltaretrovirus envelope glycoproteins and their receptors
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Article
Lamotrigine Is Neuroprotective in the Energy Deficiency Model of MPTP Intoxicated Mice
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) inhibits the mitochondrial complex I of the respiratory chain. This results in ATP and ion homeostasis disturbances, which lead to selective death of the...
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Wolcott-Rallison syndrome: a case with endocrine and exocrine pancreatic deficiency and pancreatic hypotrophy
