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Open AccessVisible light-induced switching of soft matter materials properties based on thioindigo photoswitches
Thioindigos are visible light responsive photoswitches with excellent spatial control over the conformational change between their trans- and cis- isomers. However, they possess limited solubility in all conventi...
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Open AccessTrajectory of immune evasion and cancer progression in hepatocellular carcinoma
Immune evasion is key to cancer initiation and later at metastasis, but its dynamics at intermediate stages, where potential therapeutic interventions could be applied, is undefined. Here we show, using multi-...
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Open AccessAuthor Correction: Intratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-21556-y.
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Article
Open AccessIntratumoural immune heterogeneity as a hallmark of tumour evolution and progression in hepatocellular carcinoma
The clinical relevance of immune landscape intratumoural heterogeneity (immune-ITH) and its role in tumour evolution remain largely unexplored. Here, we uncover significant spatial and phenotypic immune-ITH fr...
