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  1. Article

    Open Access

    L-carnitine does not improve valproic acid poisoning management: a cohort study with toxicokinetics and concentration/effect relationships

    Valproic acid (VPA) poisoning is responsible for life-threatening neurological and metabolic impairments. Despite only low-level evidence of effectiveness, L-carnitine has been used for years to prevent or rev...

    Philippe Nguyen, Lucie Chevillard, Ahmed S. Gouda in Annals of Intensive Care (2022)

  2. No Access

    Reference Work Entry In depth

    Environmental Noise in Gravitational-Wave Interferometers

    The first 20 years of operation of gravitational-wave interferometers have shown that, despite the high degree of isolation, detectors are affected by influences from the surrounding environment. Seismic, acou...

    Irene Fiori, Anamaria Effler, Philippe Nguyen in Handbook of Gravitational Wave Astronomy (2022)

  3. No Access

    Article

    A pilot study of procoagulant platelet extracellular vesicles and P-selectin increase during induction treatment in acute lymphoblastic leukaemia paediatric patients: two new biomarkers of thrombogenic risk?

    In paediatric acute lymphoblastic leukaemia (ALL), focus has shifted towards preventing treatment-related complications, including venous thromboembolism, the cause of significant mortality and morbidity. To b...

    Claire Pluchart, Coralie Barbe, Gael Poitevin in Journal of Thrombosis and Thrombolysis (2021)

  4. No Access

    Article

    AgeR deletion decreases soluble fms-like tyrosine kinase 1 production and improves post-ischemic angiogenesis in uremic mice

    Peripheral arterial disease occurs more frequently and has a worse prognosis in patients with chronic kidney disease (CKD). The receptor for advanced glycation end products (RAGE) is involved in multiple aspec...

    Vincent Dupont, Rida Al-Rifai, Gael Poitevin, Jeremy Ortillon in Angiogenesis (2021)

  5. No Access

    Chapter and Conference Paper

    Industrial Cyber Security at the Network Edge: The BRAINE Project Approach

    This work presents the BRAINE Project approaches and solutions to enable AI-empowered industrial applications to efficiently and securely operate at the network edge. First, two use cases are presented to high...

    Francesco Paolucci, Pavel Burget in Impact and Opportunities of Artificial Int… (2021)

  6. No Access

    Living Reference Work Entry In depth

    Environmental Noise in Gravitational-Wave Interferometers

    The first 20 years of operation of gravitational-wave interferometers have shown that, despite the high degree of isolation, detectors are affected by influences from the surrounding environment. Seismic, acou...

    Irene Fiori, Anamaria Effler, Philippe Nguyen in Handbook of Gravitational Wave Astronomy

  7. Article

    Open Access

    Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring

    COVID-19 is an infection induced by the SARS-CoV-2 coronavirus, and severe forms can lead to acute respiratory distress syndrome (ARDS) requiring intensive care unit (ICU) management. Severe forms are associat...

    Sophie Susen, Charles Ambroise Tacquard, Alexandre Godon in Critical Care (2020)

  8. Article

    Open Access

    In vivo efficacy of endothelial growth medium stimulated mesenchymal stem cells derived from patients with critical limb ischemia

    Cell therapy has been proposed for patients with critical limb ischemia (CLI). Autologous bone marrow derived cells (BMCs) have been mostly used, mesenchymal stem cells (MSCs) being an alternative. The aim of ...

    Rida Al-Rifai, Philippe Nguyen, Nicole Bouland in Journal of Translational Medicine (2019)

  9. No Access

    Article

    Vincristine induces procoagulant activity of the human lymphoblastic leukemia cell line Jurkat through the release of extracellular vesicles

    Thromboembolic events are frequent and serious complications of acute lymphoblastic leukaemia treatment. The importance of chemotherapy in the pathogenesis of this increased risk is enhanced by the fact that t...

    Claire Pluchart, Gael Poitevin in Journal of Thrombosis and Thrombolysis (2019)

  10. Article

    Open Access

    Proceedings of Réanimation 2017, the French Intensive Care Society International Congress

    Wulfran Bougouin, Eloi Marijon, Benjamin Planquette in Annals of Intensive Care (2017)

  11. Article

    Open Access

    Argatroban in the management of heparin-induced thrombocytopenia: a multicenter clinical trial

    The aim of this study was to collect data in France in patients with heparin-induced thrombocytopenia who required parenteral anticoagulation and for whom other non-heparin anticoagulant therapies were contrai...

    Brigitte Tardy-Poncet, Philippe Nguyen, Jean-Claude Thiranos in Critical Care (2015)

  12. No Access

    Chapter

    Physically Unclonable Function: Principle, Design and Characterization of the Loop PUF

    This chapter presents a novel Physically Unclonable Function PUF called “Loop PUF” (LPUF) which has been studied specifically to be easy to design, lightweight and reliable. The LPUF principle is based on a lo...

    Zouha Cherif, Jean-Luc Danger, Florent Lozac’h in Trusted Computing for Embedded Systems (2015)

  13. No Access

    Article

    Pharmacokinetics of fondaparinux 1.5 mg once daily in a real-world cohort of patients with renal impairment undergoing major orthopaedic surgery

    Fondaparinux, a selective activator factor X (factor Xa) inhibitor, is effective and safe for preventing venous thromboembolism after major orthopaedic surgery (MOS) at the once-daily subcutaneous dose of 2.5 ...

    Xavier Delavenne, Paul Zufferey in European Journal of Clinical Pharmacology (2012)

  14. No Access

    Chapter and Conference Paper

    System-Level Methods to Prevent Reverse-Engineering, Cloning, and Trojan Insertion

    The reverse-engineering (RE) is a real threat on high-value circuits. Many unitary solutions have been proposed to make RE difficult. Most of them are low-level, and thus costly to design and to implement. In ...

    Sylvain Guilley, Jean-Luc Danger in Information Systems, Technology and Manage… (2012)

  15. No Access

    Article

    IL-10 modulates fondaparinux inhibition of monocyte-induced thrombin generation

    In addition to its established immuno-regulating capacity, the anti-inflammatory cytokine interleukin (IL)-10 exerts direct effects on coagulation. IL-10 down regulates the expression of tissue factor (TF) and...

    Sonia Ben-Hadj-Khalifa, Nathalie Hézard in Journal of Thrombosis and Thrombolysis (2011)

  16. No Access

    Article

    Differential inhibitory effect of fondaparinux on the procoagulant potential of intact monocytes and monocyte-derived microparticles

    Monocytes and monocyte-derived microparticles (MMPs) play a major role in acute coronary syndrome (ASC). Activated monocytes (ac-M) and MMPs support thrombin generation via tissue factor (TF). The aim of this ...

    Sonia Ben-Hadj-Khalifa-Kechiche, Nathalie Hezard in Journal of Thrombosis and Thrombolysis (2010)

  17. No Access

    Chapter and Conference Paper

    A Theoretical Framework for Watermarking of Compressed Signals

    Nowadays, digital video, audio and multimedia signals are mostly transported, stored, exchanged, broadcast in compressed form. Thus, most of the multimedia processing operations, amongst them watermarking, sha...

    Séverine Baudry, Philippe Nguyen in Digital Watermarking (2008)

  18. Article

    Canadian survey on the practice of regional anesthesia for cardiac surgery

    Philippe Nguyen, Nicolas Noiseux, David Bracco in Canadian Journal of Anaesthesia (2007)

  19. No Access

    Chapter

    Prise en charge en rééducation fonctionnelle des patients opérés de métastases vertébrales

    Le patient atteint de localisations métastatiques rachidiennes a souvent suivi un parcours long et éprouvant. Une fois opéré, il cours faut ensuite lui proposer une réadaptation optimale.

    Christine Ravaud, Roselyne De Munico, Philippe Nguyen in Métastases vertébrales (2007)

  20. No Access

    Article

    Prevention of vascular thrombosis by human purified protein C concentrate in a patient with familial PC deficiency undergoing renal transplantation

    Olivier Toupance, Philippe Nguyen, Bernard Brandt in Transplant International (1994)