6 Result(s)

Article

Correction: Circulating levels of soluble Dipeptidylpeptidase-4 are reduced in human subjects hospitalized for severe COVID-19 infections

Kristina Schlicht, Nathalie Rohmann, Corinna Geisler… in International Journal of Obesity (2022)

Article

Mutational mechanisms sha** the coding and noncoding genome of germinal center derived B-cell lymphomas

B cells have the unique property to somatically alter their immunoglobulin (IG) genes by V(D)J recombination, somatic hypermutation (SHM) and class-switch recombination (CSR). Aberrant targeting of these mecha...

Daniel Hübschmann, Kortine Kleinheinz, Rabea Wagener, Stephan H. Bernhart… in Leukemia (2021)

Article

Circulating levels of soluble Dipeptidylpeptidase-4 are reduced in human subjects hospitalized for severe COVID-19 infections

Dipeptidylpeptidase (DPP)-4 is a key regulator of the incretin system. For several years DPP-4 inhibitors in addition to GLP-1 analogues are of major importance in the clinical management of obesity and type 2...

Kristina Schlicht, Nathalie Rohmann, Corinna Geisler… in International Journal of Obesity (2020)

Article

Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases

Interleukin-6 (IL-6) production and signalling are increased in the inflamed mucosa in inflammatory bowel diseases (IBD). As published serum levels of IL-6 and its soluble receptors sIL-6R and sgp130 in IBD ar...

Susanna Nikolaus, Georg H. Waetzig… in International Journal of Colorectal Disease (2018)

Article

Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model

Hematopoietic stem cell transplantation is increasingly performed for hematologic diseases. As a major side effect, acute graft versus host disease (GvHD) with serious gastrointestinal symptoms including diarr...

Rainer Noth, Julia Lange-Grumfeld, Eckhard Stüber… in BMC Gastroenterology (2011)

Article

Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer

Variation in genes involved in the innate immune response may play a role in the predisposition to colorectal cancer (CRC). Several polymorphisms of the CARD15 gene (caspase activating recruitment domain, member ...

Nikolaus Möckelmann, Witigo von Schönfels, Stephan Buch… in BMC Gastroenterology (2009)