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  1. Article

    Open Access

    Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases

    Interleukin-6 (IL-6) production and signalling are increased in the inflamed mucosa in inflammatory bowel diseases (IBD). As published serum levels of IL-6 and its soluble receptors sIL-6R and sgp130 in IBD ar...

    Susanna Nikolaus, Georg H. Waetzig… in International Journal of Colorectal Disease (2018)

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  2. Article

    Open Access

    Pharmacological inhibition of IL-6 trans-signaling improves compromised fracture healing after severe trauma

    Patients with multiple injuries frequently suffer bone fractures and are at high risk to develop fracture healing complications. Because of its key role both in systemic posttraumatic inflammation and fracture...

    Kathrin Kaiser, Katja Prystaz, Anna Vikman… in Naunyn-Schmiedeberg's Archives of Pharmaco… (2018)

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  3. No Access

    Article

    Genetic variation in DLG5 is associated with inflammatory bowel disease

    Crohn disease and ulcerative colitis are two subphenotypes of inflammatory bowel disease (IBD), a complex disorder resulting from gene-environment interaction. We refined our previously defined linkage region ...

    Monika Stoll, Brit Corneliussen, Christine M Costello, Georg H Waetzig… in Nature Genetics (2004)

  4. No Access

    Article

    Efficient regeneration of Sphagnum fallax from isolated protoplasts

    While the in vitro clonal propagation of peat mosses (Sphagnaceae) in bioreactors has been established since the late 1980s, it has never been possible to regenerate Sphagnum species from isolated protoplasts, wh...

    Amla Batra, Horst Binding, Susanne Rasmussen… in In Vitro Cellular & Developmental Biology … (2003)