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    Article

    Deep brain stimulation for obsessive–compulsive disorder: a crisis of access

    Deep brain stimulation is an effective treatment for obsessive–compulsive disorder but is rarely used. Action is needed by psychologists, psychiatrists and insurers so that patients with otherwise intractable ...

    Veerle Visser-Vandewalle, Pablo Andrade, Philip E. Mosley in Nature Medicine (2022)

  2. Article

    Open Access

    ‘Woe Betides Anybody Who Tries to Turn me Down.’ A Qualitative Analysis of Neuropsychiatric Symptoms Following Subthalamic Deep Brain Stimulation for Parkinson’s Disease

    Deep brain stimulation (DBS) of the subthalamic nucleus (STN) for the treatment of Parkinson’s disease (PD) can lead to the development of neuropsychiatric symptoms. These can include harmful changes in mood a...

    Philip E. Mosley, Katherine Robinson, Terry Coyne, Peter Silburn in Neuroethics (2021)

  3. Article

    Open Access

    A randomised, double-blind, sham-controlled trial of deep brain stimulation of the bed nucleus of the stria terminalis for treatment-resistant obsessive-compulsive disorder

    Deep brain stimulation (DBS) is a promising treatment for severe, treatment-resistant obsessive-compulsive disorder (OCD). Here, nine participants (four females, mean age 47.9 ± 10.7 years) were implanted with...

    Philip E. Mosley, François Windels, John Morris, Terry Coyne in Translational Psychiatry (2021)

  4. Article

    Open Access

    Subjective estimates of uncertainty during gambling and impulsivity after subthalamic deep brain stimulation for Parkinson’s disease

    Subthalamic deep brain stimulation (DBS) for Parkinson’s disease (PD) may modulate chronometric and instrumental aspects of choice behaviour, including motor inhibition, decisional slowing, and value sensitivi...

    Saee Paliwal, Philip E. Mosley, Michael Breakspear, Terry Coyne in Scientific Reports (2019)

  5. Article

    Open Access

    Caregiver burden and caregiver appraisal of psychiatric symptoms are not modulated by subthalamic deep brain stimulation for Parkinson’s disease

    Subthalamic deep brain stimulation is an advanced therapy that typically improves quality of life for persons with Parkinson’s disease (PD). However, the effect on caregiver burden is unclear. We recruited 64 ...

    Philip E. Mosley, Michael Breakspear, Terry Coyne, Peter Silburn in npj Parkinson's Disease (2018)