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Article
Open AccessThe effect of acute exercise on circulating immune cells in newly diagnosed breast cancer patients
The role of exercise in cancer prevention and control is increasingly recognized, and based on preclinical studies, it is hypothesized that mobilization of leukocytes plays an important role in the anti-tumor ...
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Article
Open AccessGPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation
Dissecting the pathways regulating the adaptive immune response in atherosclerosis is of particular therapeutic interest. Here we report that the lipid G-protein-coupled receptor GPR55 is highly expressed by s...
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Article
Open AccessPro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis – Tampere Vascular Study
α-melanocyte-stimulating hormone (α-MSH) is processed from pro-opiomelanocortin (POMC) and mediates anti-inflammatory actions in leukocytes. α-MSH also promotes macrophage reverse cholesterol transport by indu...
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Article
Comparison of Somatostatin Receptor 2-Targeting PET Tracers in the Detection of Mouse Atherosclerotic Plaques
Rupture-prone atherosclerotic plaques are characterized by accumulation of macrophages, which have shown to express somatostatin type 2 receptors. We aimed to investigate whether somatostatin receptor-targetin...