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    Article

    M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination

    In this study, the authors show that oligodendrocyte differentiation and remyelination after a CNS lesion coincides with a switch in microglial/macrophage polarization from a pro-inflammatory, M1, phenotype to...

    Veronique E Miron, Amanda Boyd, **g-Wei Zhao, Tracy J Yuen in Nature Neuroscience (2013)

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    Open Access

    The AppNL-G-F mouse retina is a site for preclinical Alzheimer’s disease diagnosis and research

    In this study, we report the results of a comprehensive phenoty** of the retina of the AppNL-G-F mouse. We demonstrate that soluble Aβ accumulation is present in the retina of these mice early in life and progr...

    Marjan Vandenabeele, Lien Veys, Sophie Lemmens in Acta Neuropathologica Communications (2021)

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    Chapter

    Retinal Imaging and Functional Biomarkers of Huntington’s Disease

    The retina shares a common embryological origin with the brain and both organs have numerous anatomical and functional commonalities. The retina is the only portion of the central nervous system that is optica...

    Abera Saeed, Peter van Wijngaarden in Biomarkers for Huntington's Disease (2023)