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Article
Proposed mechanism for increased COVID-19 mortality in patients with decompensated cirrhosis
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Article
Open AccessThe small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice
There is no established medical therapy to treat biliary fibrosis resulting from chronic inflammation in the biliary tree. We have recently shown that liver-specific over-expression of angiotensin converting e...
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Article
The role of the gut microbiota in NAFLD
The incidence of fatty liver disease, and its complications of inflammation, fibrosis and liver cancer, is increasing
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Article
Diagnosis and management of acute variceal bleeding: Asian Pacific Association for Study of the Liver recommendations
Acute variceal bleeding (AVB) is a medical emergency and associated with a mortality of 20% at 6 weeks. Significant advances have occurred in the recent past and hence there is a need to update the existing co...
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Article
Open AccessChanges in the renin angiotensin system during the development of colorectal cancer liver metastases
Blockade of the renin angiotensin system (RAS) via angiotensin I converting enzyme (ACE) inhibition reduces growth of colorectal cancer (CRC) liver metastases in a mouse model. In this work we defined the expr...
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Article
Primary prophylaxis of gastroesophageal variceal bleeding: consensus recommendations of the Asian Pacific Association for the Study of the Liver
The Asian Pacific Association for the Study of the Liver (APASL) set up a Working Party on Portal Hypertension in 2002, with a mandate to develop consensus guidelines on various clinical aspects of portal hype...
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Article
A Study of Galactose Intolerance in Human and Rat Liver In Vivo by 31P Magnetic Resonance Spectroscopy
ABSTRACT: An oral load of 20 mg/kg galactose produces significant changes in the 31P magnetic resonance spectrum of the liver of a galactosemic patient. The peak at 5.2 ppm (which includes inorganic phosphate and...