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Article
Open AccessDrivers and impact of the early silent invasion of SARS-CoV-2 Alpha
SARS-CoV-2 variants of concern (VOCs) circulated cryptically before being identified as a threat, delaying interventions. Here we studied the drivers of such silent spread and its epidemic impact to inform fut...
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Article
How should we speak about years of life lost (YLL) values?
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Article
From individual-based epidemic models to McKendrick-von Foerster PDEs: a guide to modeling and inferring COVID-19 dynamics
We present a unifying, tractable approach for studying the spread of viruses causing complex diseases requiring to be modeled using a large number of types (e.g., infective stage, clinical state, risk factor c...
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Article
Open AccessFixation probabilities in populations under demographic fluctuations
We study the fixation probability of a mutant type when introduced into a resident population. We implement a stochastic competitive Lotka–Volterra model with two types and intra- and interspecific competition...
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Article
Open AccessLimits of noise for autoregulated gene expression
Gene expression is influenced by extrinsic noise (involving a fluctuating environment of cellular processes) and intrinsic noise (referring to fluctuations within a cell under constant environment). We study t...