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Article
Open AccessGeneration of nanobodies from transgenic ‘LamaMice’ lacking an endogenous immunoglobulin repertoire
Due to their exceptional solubility and stability, nanobodies have emerged as powerful building blocks for research tools and therapeutics. However, their generation in llamas is cumbersome and costly. Here, b...
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Article
Open AccessMyocardial strain assessment in the human fetus by cardiac MRI using Doppler ultrasound gating and feature tracking
Assessment of myocardial strain by feature tracking magnetic resonance imaging (FT-MRI) in human fetuses with and without congenital heart disease (CHD) using cardiac Doppler ultrasound (DUS) gating.
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Article
Open AccessLongitudinal follow-up by MR angiography reveals progressive dilatation of the distal aorta after aortic root replacement in Marfan syndrome
To define and compare growth rates of the distal aorta in Marfan patients with and without aortic root replacement using serial MR angiography (MRA).
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Article
Open AccessAssessment of aortic diameter in Marfan patients: intraindividual comparison of 3D-Dixon and 2D-SSFP magnetic resonance imaging
To compare the accuracy and precision of 3D-Dixon and 2D-SSFP MR-imaging for assessment of aortic diameter in Marfan patients.
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Article
Open AccessValidation of 4D flow cardiovascular magnetic resonance in TIPS stent grafts using a 3D-printed flow phantom
Four-dimensional (4D) flow cardiovascular magnetic resonance (CMR) is feasible for portal blood flow evaluation after placement of transjugular intrahepatic portosystemic shunts (TIPS) in patients with liver c...
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Article
Open AccessComparison of cine cardiac magnetic resonance and echocardiography derived diameters of the aortic root in a large population-based cohort
Transthoracic echocardiography (TTE) and cine cardiac magnetic resonance imaging (CMR) are established imaging methods of the aortic root. We aimed to evaluate the comparability of measurements in TTE and stan...
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Article
Open AccessCan homogeneous, lipomatous tumors be primarily resected without biopsy? A retrospective analysis of 240 tumors
According to guidelines, every soft tissue tumor (STT) larger than 3 cm should be biopsied before definitive resection. Advances in magnetic resonance imaging (MRI) improve the possibility to give a provisiona...
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Article
Open AccessRadiation dose reduction during adrenal vein sampling using a new angiographic imaging technology
To compare the patient radiation doses during angiographic selective adrenal vein sampling (AVS) before and after an imaging technology upgrade. In this retrospective single-center-study, cumulative air kerma ...
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Article
Open AccessAnterior Pituitary Volume in Patients with Transfusion Dependent Anemias: Volumetric Approaches and Relation to Pituitary MRI‑R2
Anterior pituitary iron overload and volume shrinkage is common in patients with transfusion-dependent anemia and associated with growth retardation and hypogonadotropic hypogonadism. We investigated the accur...
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Open AccessInsights into diastolic function analyses using cardiac magnetic resonance imaging: impact of trabeculae and papillary muscles
This cardiovascular magnetic resonance (CMR) study investigates the impact of trabeculae and papillary muscles (TPM) on diastolic function parameters by differentiation of the time-volume curve. Differentiatio...
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Open AccessAuthor Correction: Phenoty** spinal abnormalities in patients with Neurofibromatosis type 1 using whole-body MRI
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Article
Open AccessPhenoty** spinal abnormalities in patients with Neurofibromatosis type 1 using whole-body MRI
Neurofibromatosis Type 1 (NF1) has been reported to be associated with a variety of spinal abnormalities. The purpose of this study was to quantify the prevalence of spinal abnormalities in a collective of NF1...
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Article
Open AccessCardiovascular magnetic resonance demonstrates structural cardiac changes following transjugular intrahepatic portosystemic shunt
Transjugular intrahepatic portosystemic shunt (TIPS) reduces portal hypertension in patients with liver cirrhosis. The exact cardiac consequences of subsequent increase of central blood volume are unknown. Car...
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Article
Open AccessImpact of chest wall deformity on cardiac function by CMR and feature-tracking strain analysis in paediatric patients with Marfan syndrome
To evaluate systolic cardiac dysfunction in paediatric MFS patients with chest wall deformity using cardiac magnetic resonance (CMR) imaging and feature-tracking strain analysis.
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Article
Feasibility and optimization of ultra-short echo time MRI for improved imaging of IVC-filters at 3.0 T
To determine the feasibility of ultra-short echo time (UTE) MRA for assessment of inferior vena cava (IVC) filters and evaluate the impact of different imaging protocols at 3.0 T, using conventional Cartesian ...
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Article
Open AccessReliability of non-contrast magnetic resonance angiography-derived aortic diameters in Marfan patients: comparison of inner vs. outer vessel wall measurements
Aortic diameter measurements play a crucial role for the indication of aortic root surgery in Marfan patients. However, for magnetic resonance angiography (MRA)-derived measurements, there is no consensus on w...
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Open Access4D flow cardiovascular magnetic resonance for monitoring of aortic valve repair in bicuspid aortic valve disease
Aortic valve repair has become a treatment option for adults with symptomatic bicuspid (BAV) or unicuspid (UAV) aortic valve insufficiency. Our aim was to demonstrate the feasibility of 4D flow cardiovascular ...
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Genetisch bedingte Aortenerkrankungen
Thorakale Aortenaneurysmen und Aortendissektionen entstehen in etwa 80 % durch arterielle Hypertonie und Atherosklerose, und in etwa 20 % durch genetische Erkrankungen wie das Marfan-Syndrom oder eine bikuspid...
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Response to: “Letter to the editor: Mesoaxial synostotic syndactyly with phalangeal reduction (MSSD): syndactyly type IX”
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Lama-Antikörper helfen bei der Erforschung neuer Krebs-Therapie