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Article
Open AccessOptimization of the Air Cleaning Properties of Fog
Fog droplets are very often used as a cleaning agent when air pollution can be dangerous for health conditions and ecosystem. This work presents a new system to optimize the cleaning properties of fog by tunin...
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Article
New N- and C-modified RGD-hemorphins as potential biomedical application on Ti-surface materials: synthesis, characterization and antinociceptive activity
This manuscript presented the synthesis and characterization of two new N- and C-modified analogues of VV-hemorphin-7 containing RGD (Arg–Gly–Asp) residues as potential nociceptive agents and bioactive materia...
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Article
Investigation of the structure–activity relationship in a series of new LVV- and VV-hemorphin-7 analogues designed as potential anticonvulsant agents
In the present study, a series of new analogues of both LVV- and VV-hemorphin-7 have been synthesized and characterized. They were modified at the N- and C-terminus with varied amino acids (Ile, D-Leu, D-Val, D-P...
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Article
Open AccessMachine learning identifies candidates for drug repurposing in Alzheimer’s disease
Clinical trials of novel therapeutics for Alzheimer’s Disease (AD) have consumed a large amount of time and resources with largely negative results. Repurposing drugs already approved by the Food and Drug Admi...
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Article
VV-hemorphin-5 analogue for trace copper determination in water samples
Natural and anthropogenic sources produce mainly metal ions which can be accumulated in sediments that have a significant environmental impact on local areas, especially for their river water quality. The envi...
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Article
Structure–activity relationship study on new hemorphin-4 analogues containing steric restricted amino acids moiety for evaluation of their anticonvulsant activity
In the present study, several new analogues of hemorphin-4, modified with unnatural conformationally restricted amino acids followed the structure Aaa–Tyr–Xxx–Trp–Thr–NH2, where Aaa is the low-molecular-weight li...
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Article
Potential anticonvulsant activity of novel VV-hemorphin-7 analogues containing unnatural amino acids: synthesis and characterization
Herein, some new analogues of VV-hemorphin-7, modified at position 4 and 7 by the unnatural amino acids followed the structure Val-Val-Tyr-Xxx-Trp-Thr-Yyy-Arg-Phe-NH2, where Xxx is Ac5c (1-aminocyclopentanecarbox...
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Chapter
The Myth of Victimization in Macedonian History Textbooks (1991–2018)
This paper studies historical narratives of suffering present in history textbooks for primary and secondary education in the Republic of Macedonia since the proclamation of its independence in 1991. Using con...
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Article
Synthesis, characterization and anticonvulsant activity of new series of N-modified analogues of VV-hemorphin-5 with aminophosphonate moiety
A new series of N-modified analogues of the VV-hemorphin-5 with aminophosphonate moiety have been synthesized, characterized and investigated for anticonvulsant activity. The novel peptide analogues were prepared...
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Chapter
From Bucharest 1913 to Bucharest 2008: The Image of the Balkan Wars in Macedonian Historiography and Public Discourse
This chapter deals with the complex image of the Balkan Wars in Macedonian society. It examines the historiographic production of the wars in the Yugoslav and post-Yugoslav context as well as the public discou...
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Article
Synthesis and analgesic effects of novel β2-tryptophan hexapeptide analogs
Aiming to develop more potent analgesic substances a new series of hexapeptides containing β2-tryptophan analogues was synthesized. The Trp in position 4 and 5, respectively in Ac-Arg-Phe-Met-Trp-Met-Lys-NH2 (opi...
