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  1. Article

    Open Access

    Plasma proteome of growing tumors

    Early detection of cancer is vital for the best chance of successful treatment, but half of all cancers are diagnosed at an advanced stage. A simple and reliable blood screening test applied routinely would th...

    Shashi Gupta, Matthew J. Westacott, Deborah G. Ayers, Sophie J. Weiss… in Scientific Reports (2023)

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  2. No Access

    Article

    Impact of genetic variation in CYP2C19, CYP2D6, and CYP3A4 on oxycodone and its metabolites in a large database of clinical urine drug tests

    Urine drug testing (UDT) is a tool for monitoring drug use, including oxycodone. While variation in cytochrome P450 (CYP) genes is known to alter oxycodone metabolism, its impact on UDT results of oxycodone and i...

    Guang-dan Zhu, Penn Whitley, Leah LaRue, Brandon Adkins… in The Pharmacogenomics Journal (2022)

  3. Article

    Open Access

    Improved microarray gene expression profiling of virus-infected cells after removal of viral RNA

    Sensitivity and accuracy are key points when using microarrays to detect alterations in gene expression under different conditions. Critical to the acquisition of reliable results is the preparation of the RNA...

    Matthijs Raaben, Penn Whitley, Diane Bouwmeester, Robert A Setterquist… in BMC Genomics (2008)

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  4. Article

    Genetics of α-amanitin resistance in a natural population of Drosophila melanogaster

    The genetic basis of variation in resistance to natural toxins is of interest for both ecological and evolutionary genetics. The wide variety of larval resources used by Drosophila, both within and between specie...

    David J Begun, Penn Whitley in Heredity (2000)

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