31 Result(s)
within
Peng Cao
Biomedicine
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Article
Open AccessEpigallocatechin gallate modulates ferroptosis through downregulation of tsRNA-13502 in non-small cell lung cancer
Ferroptosis, an iron-dependent regulated cell death mechanism, holds significant promise as a therapeutic strategy in oncology. In the current study, we explored the regulatory effects of epigallocatechin gall...
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Article
Correction to: Brain Mechanisms Underlying Panic Attack and Panic Disorder
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Article
Brain Mechanisms Underlying Panic Attack and Panic Disorder
Panic disorder is a psychiatric disorder characterized by recurrent panic attacks, with a prevalence of ~ 4% in the general population, causing heavy personal and socioeconomic burdens. The similarities of ani...
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A molecularly defined amygdala-independent tetra-synaptic forebrain-to-hindbrain pathway for odor-driven innate fear and anxiety
Fear-related disorders (for example, phobias and anxiety) cause a substantial public health problem. To date, studies of the neural basis of fear have mostly focused on the amygdala. Here we identify a molecul...
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Neural Mechanisms Underlying the Coughing Reflex
Breathing is an intrinsic natural behavior and physiological process that maintains life. The rhythmic exchange of gases regulates the delicate balance of chemical constituents within an organism throughout it...
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Open AccessGinseng-derived nanoparticles reprogram macrophages to regulate arginase-1 release for ameliorating T cell exhaustion in tumor microenvironment
Lines of evidence indicated that, immune checkpoints (ICs) inhibitors enhanced T cell immune response to exert anti-tumor effects. However, T cell exhaustion has been so far a major obstacle to antitumor immun...
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Open AccessExosomal ACADM sensitizes gemcitabine-resistance through modulating fatty acid metabolism and ferroptosis in pancreatic cancer
This study aimed to evaluate the potential of exosomes from cancer cells to predict chemoresistance in pancreatic cancer (PC) and explore the molecular mechanisms through RNA-sequencing and mass spectrometry. ...
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Up-regulation of microglial chemokine CXCL12 in anterior cingulate cortex mediates neuropathic pain in diabetic mice
Diabetic patients frequently experience neuropathic pain, which currently lacks effective treatments. The mechanisms underlying diabetic neuropathic pain remain unclear. The anterior cingulate cortex (ACC) is ...
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Angiotensin Type 2 Receptor Pharmacological Agonist Relieves Neurocognitive Deficits via Reducing Neuroinflammation and Microglial Engulfment of Dendritic Spines
Mechanically ventilated patients suffering critical illness are at high risk of develo** neurocognitive impairments. Angiotensin type 2 receptor (AGTR2) has been demonstrated to be anti-inflammatory and neur...
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Open AccessNeurocircuitry of Predatory Hunting
Predatory hunting is an important type of innate behavior evolutionarily conserved across the animal kingdom. It is typically composed of a set of sequential actions, including prey search, pursuit, attack, an...
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Open AccessThe Superior Colliculus: Cell Types, Connectivity, and Behavior
The superior colliculus (SC), one of the most well-characterized midbrain sensorimotor structures where visual, auditory, and somatosensory information are integrated to initiate motor commands, is highly cons...
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Modeling global and local label correlation with graph convolutional networks for multi-label chest X-ray image classification
The diagnosis of chest diseases is a challenging task for assessing thousands of radiology subjects. Their diagnosis decisions heavily rely on the expert radiologists’ manual annotations. It is important to de...
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Modeling the dynamic brain network representation for autism spectrum disorder diagnosis
The dynamic functional connectivity analysis provides valuable information for understanding functional brain activity underlying different cognitive processes. Modeling spatio-temporal dynamics in functional ...
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Open AccessA promising Prognostic risk model for advanced renal cell carcinoma (RCC) with immune-related genes
Renal cell carcinoma (RCC) is a third most common tumor of the urinary system. Nowadays, Immunotherapy is a hot topic in the treatment of solid tumors, especially for those tumors with pre-activated immune state.
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TE-HI-GCN: An Ensemble of Transfer Hierarchical Graph Convolutional Networks for Disorder Diagnosis
Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Graph convolutional networks (GCNs) a...
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Mechanically evoked defensive attack is controlled by GABAergic neurons in the anterior hypothalamic nucleus
Innate defensive behaviors triggered by environmental threats are important for animal survival. Among these behaviors, defensive attack toward threatening stimuli (for example, predators) is often the last li...
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Open AccessTargeting strategies for oxaliplatin-induced peripheral neuropathy: clinical syndrome, molecular basis, and drug development
Oxaliplatin (OHP)-induced peripheral neurotoxicity (OIPN) is a severe clinical problem and potentially permanent side effect of cancer treatment. For the management of OIPN, accurate diagnosis and understandin...
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IL-6R blockade by chikusetsusaponin IVa butyl ester inhibits Th17 cell differentiation and ameliorates collagen-induced arthritis
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Open AccessMicroRNA-449a delays lung cancer development through inhibiting KDM3A/HIF-1α axis
It has been established that microRNA (miR)-449a is anti-tumorigenic in cancers, including lung cancer. Therefore, this study further explored miR-449a-mediated mechanism in lung cancer, mainly focusing on lys...
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Open AccessCorrection to: Antibiotics-induced intestinal dysbacteriosis caused behavioral alternations and neuronal activation in different brain regions in mice
An amendment to this paper has been published and can be accessed via the original article.
