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Article
Open AccessMutual communication between radiosensitive and radioresistant esophageal cancer cells modulates their radiosensitivity
Radiotherapy is an important treatment modality for patients with esophageal cancer; however, the response to radiation varies among different tumor subpopulations due to tumor heterogeneity. Cancer cells that...
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Article
Open AccessChemical-induced phase transition and global conformational reorganization of chromatin
Chemicals or drugs can accumulate within biomolecular condensates formed through phase separation in cells. Here, we use super-resolution imaging to search for chemicals that induce phase transition within chr...
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Article
Open AccessAssociation of MLL3 and TGF-β signaling gene polymorphisms with the susceptibility and prognostic outcomes of Stanford type B aortic dissection
This study aims to investigate the association of lysine methyltransferase 2 C (MLL3) and transforming growth factor β (TGF-β) signaling-related gene polymorphisms with the susceptibility of Stanford type B ao...
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Article
Functional traits and its variation linked to species’ degree of isohydry in subtropical regions with high heterogeneity
The degree of species’ isohydry determined by the stringency degree of stomatal regulation is commonly used to classify species’ drought response strategies. The aim of our study is to determine the linkages o...
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Article
Association of gene polymorphisms in MYH11 and TGF-β signaling with the susceptibility and clinical outcomes of DeBakey type III aortic dissection
To investigate the association of myosin heavy chain protein 11 (MYH11) and transforming growth factor β signaling-related gene polymorphisms with the susceptibility of DeBakey type III aortic dissection (AD) ...
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Article
Diffusion kurtosis imaging for assessing endometrial fibrosis: a preliminary clinical study
To investigate the feasibility of using diffusion kurtosis imaging (DKI) for the assessment of endometrial fibrosis.
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Article
Open AccessAssociation of gene polymorphisms in FBN1 and TGF-β signaling with the susceptibility and prognostic outcomes of Stanford type B aortic dissection
This study is aimed at investigating the association of Fibrillin-1 (FBN1) and transforming growth factor β (TGF-β) signaling-related gene polymorphisms with the susceptibility of Stanford type B aortic dissectio...
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Article
Open AccessDown-regulation of PBK inhibits proliferation of human endometrial stromal cells in thin endometrium
Thin endometrium (TE) is a challenging clinical issue in the reproductive medicine characterized by inadequate endometrial thickness, poor response to estrogen and no effective treatments currently. At present...
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Article
Open AccessNoninvasive assessment of endometrial fibrosis in patients with intravoxel incoherent motion MR imaging
Recently, few noninvasive methods have been reported to evaluate endometrial fibrosis. Our study was to investigate the feasibility of intravoxel incoherent motion (IVIM) MR imaging in the detection of endomet...
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Article
Open AccessΔNp63α-induced DUSP4/GSK3β/SNAI1 pathway in epithelial cells drives endometrial fibrosis
Epithelial homeostasis plays an essential role in maintaining endometrial function. But the epithelial role in endometrial fibrosis has been less studied. Previously, we showed that ectopic expression of ΔNp63...
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Article
Open AccessComparison between Fissure Sealant and Fluoride Varnish on Caries Prevention for First Permanent Molars: a Systematic Review and Meta-analysis
The high prevalence and heavy socio-economic burden for caries of first permanent molars (FPMs) make the prevention of this disease a major public health goal. Current guidelines recommend a preference of fiss...
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Article
Collagen-binding basic fibroblast growth factor improves functional remodeling of scarred endometrium in uterine infertile women: a pilot study
Intrauterine adhesion (IUA) is a common cause of uterine infertility and one of the most severe clinical features is endometrial fibrosis namely endometrial scarring for which there are few cures currently. Bl...
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Article
Inter-frame video image generation based on spatial continuity generative adversarial networks
This paper proposes a method for generating inter-frame video images based on spatial continuity generative adversarial networks (SC-GANs) to smooth the playing of low-frame rate videos and to clarify blurry i...
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Article
Open AccessVascular endothelial growth factor 165 inhibits pro-fibrotic differentiation of stromal cells via the DLL4/Notch4/smad7 pathway
Endometrial fibrosis is the main pathological feature of Asherman’s syndrome (AS), which is the leading cause of uterine infertility. Much is known about the expression of VEGF165 in luminal/glandular epitheli...
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Article
Elaborate differences between trees and understory plants in the deployment of fine roots
Spatially segregating root systems is a fundamental mechanism by which plants can avoid competition for resources. Understory roots contribute substantially to total forest fine-root biomass, but the strategy ...
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Article
Fascin-1 Contributes to Neuropathic Pain by Promoting Inflammation in Rat Spinal Cord
Neuropathic pain is a complicated clinical syndrome caused by heterogeneous etiology. Despite the fact that the underlying mechanisms remain elusive, it is well accepted that neuroinflammation plays a critical...
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Article
Insulin-like Growth Factor Binding Protein6 Associated with Neuronal Apoptosis Following Intracerebral Hemorrhage in Rats
The insulin-like growth factor (IGF) system is linked to CNS pathological states. The functions of IGFs are modulated by a family of binding proteins termed insulin-like growth factor binding proteins (IGFBPs)...
