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Open AccessNatural proteome diversity links aneuploidy tolerance to protein turnover
Accessing the natural genetic diversity of species unveils hidden genetic traits, clarifies gene functions and allows the generalizability of laboratory findings to be assessed. One notable discovery made in n...
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Open AccessIntegrating transcriptional activity in genome-scale models of metabolism
Genome-scale metabolic models provide an opportunity for rational approaches to studies of the different reactions taking place inside the cell. The integration of these models with gene regulatory networks is...
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Open AccessInference and interrogation of a coregulatory network in the context of lipid accumulation in Yarrowia lipolytica
Complex phenotypes, such as lipid accumulation, result from cooperativity between regulators and the integration of multiscale information. However, the elucidation of such regulatory programs by experimental ...
