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Open AccessNatural proteome diversity links aneuploidy tolerance to protein turnover
Accessing the natural genetic diversity of species unveils hidden genetic traits, clarifies gene functions and allows the generalizability of laboratory findings to be assessed. One notable discovery made in n...
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Publisher Correction: Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis
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Cargo-specific recruitment in clathrin- and dynamin-independent endocytosis
Spatially controlled, cargo-specific endocytosis is essential for development, tissue homeostasis and cancer invasion. Unlike cargo-specific clathrin-mediated endocytosis, the clathrin- and dynamin-independent...
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Picky: a simple online PRM and SRM method designer for targeted proteomics
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Detecting actively translated open reading frames in ribosome profiling data
RiboTaper quantifies the three-nucleotide periodicity in Ribo-seq data to find translated open reading frames (ORFs). The de novo inferred set of ORFs comprehensively defines the cellular proteome across a wide e...
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Open AccessExtensive identification and analysis of conserved small ORFs in animals
There is increasing evidence that transcripts or transcript regions annotated as non-coding can harbor functional short open reading frames (sORFs). Loss-of-function experiments have identified essential devel...
