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Article

Systems approaches identify the consequences of monosomy in somatic human cells

Chromosome loss that results in monosomy is detrimental to viability, yet it is frequently observed in cancers. How cancers survive with monosomy is unknown. Using p53-deficient monosomic cell lines, we find t...

Narendra Kumar Chunduri, Paul Menges, **aoxiao Zhang… in Nature Communications (2021)