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Open AccessMicrobial abundance, activity and population genomic profiling with mOTUs2
Metagenomic sequencing has greatly improved our ability to profile the composition of environmental and host-associated microbial communities. However, the dependency of most methods on reference genomes, whic...
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Article
Publisher Correction: Enterotypes in the landscape of gut microbial community composition
In the version of this Perspective originally published, the first and last name of co-author Manimozhiyan Arumugam were switched. This has now been corrected in all versions of the Perspective.
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Environment dominates over host genetics in sha** human gut microbiota
Human gut microbiome composition is shaped by multiple factors but the relative contribution of host genetics remains elusive. Here we examine genotype and microbiome data from 1,046 healthy individuals with s...
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Enterotypes in the landscape of gut microbial community composition
Population stratification is a useful approach for a better understanding of complex biological problems in human health and wellbeing. The proposal that such stratification applies to the human gut microbiome...
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Article
Open AccessThe microbiomes of blowflies and houseflies as bacterial transmission reservoirs
Blowflies and houseflies are mechanical vectors inhabiting synanthropic environments around the world. They feed and breed in fecal and decaying organic matter, but the microbiome they harbour and transport is...
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Article
Towards standards for human fecal sample processing in metagenomic studies
Testing 21 different fecal DNA extraction protocols in multiple laboratories results in a standardized protocol with the potential to improve comparability across human gut microbiome studies.
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Salt-responsive gut commensal modulates TH17 axis and disease
A Western lifestyle with high salt consumption can lead to hypertension and cardiovascular disease. High salt may additionally drive autoimmunity by inducing T helper 17 (TH17) cells, which can also contribute to...
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Article
Open AccessTemporal and technical variability of human gut metagenomes
Metagenomics has become a prominent approach for exploring the role of the gut microbiota in human health. However, the temporal variability of the healthy gut microbiome has not yet been studied in depth usin...
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A fair comparison
