![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessSite-specific mutagenesis of Drosophila proliferating cell nuclear antigen enhances its effects on calf thymus DNA polymerase δ
We and others have shown four distinct and presumably related effects of mammalian proliferating cell nuclear antigen (PCNA) on DNA synthesis catalyzed by mammalian DNA polymerase δ(pol δ). In the presence of ...
-
Article
Intranuclear distribution of DNA topoisomerase II and chromatin
Domain-specific anti-Drosophila DNA topoisomerase II antibodies were generated, affinity purified and used for confocal laser scanning immunofluorescence microscopy. Except for the nucleolus, DNA topoisomerase II...
-
Chapter and Conference Paper
Characterization of Polyprenylation of Drosophila Nuclear Lamins
In the late 1970’s studies on the structures of peptides involved in fungi mating responses resulted in discovery of a novel post-translational modification; the covalent attachment of isoprene groups (Kamiya,...
-
Chapter
Survival Strategies of the Yeast Plasmid Two-Micron Circle
The multicopy yeast plasmid 2-micron circle uses a number of strategies to insure its persistence in its host. The plasmid confers no selective phenotype to the cell in which it is resident. Nonetheless, the p...
-
Chapter
Enzymological Characterization of Human DNA Polymerases-α and β
During the past few years, we have described the results of an extensive series of investigations of the enzymological properties of essentially homogeneous preparations of human DNA polymerases-α and β1-3 that a...
-
Chapter
Structure and Catalytic Properties of Human DNA Polymerases α and β
In this paper we shall describe some of our recent studies on the structure and catalytic properties of DNA polymerases a and 8 (1) that we have purified from cultured human KB cells and from adult human liver...