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Article
Transcription factors Oct-1 and NF-YA regulate the p53-independent induction of the GADD45 following DNA damage
The p53-regulated GADD45 gene is one of the important players in cellular response to DNA damage, and probably involved in the control of cell cycle checkpoint, apoptosis and DNA repair. There are both the p53-de...
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Article
BRCA1 activation of the GADD45 promoter
Breast cancer susceptibility gene BRCA1 has been implicated in the control of gene regulation and such regulated genes are thought to mediate the biological role of BRCA1. Overexpression of BRCA1 induces GADD45, ...