11 Result(s)

Article

Managing Risks with Newer Oral Small Molecules in Patients with Inflammatory Bowel Diseases

Treatment of Inflammatory Bowel Diseases (IBD) is challenging; thus, the need for newer therapeutic options with an oral route of administration has led to the development of novel small molecules drugs (SMDs)...

Malek Ayoub, Shivani Mattay, Andres J. Yarur… in Current Gastroenterology Reports (2024)

Article

Perianal fistulizing Crohn’s disease: Current perspectives on diagnosis, monitoring and management with a focus on emerging therapies

Crohn’s disease (CD), a chronic inflammatory bowel disorder, manifests in various phenotypes, with fistulizing perianal CD (CD-PAF) being one of its most severe phenotypes. Characterized by fistula formation a...

Jalpa Devi, David H. Ballard, Tina Aswani-Omprakash… in Indian Journal of Gastroenterology (2024)

Article

Bariatric Surgery Is Acceptably Safe in Obese Inflammatory Bowel Disease Patients: Analysis of the Nationwide Inpatient Sample

The prevalence of obesity in patients with inflammatory bowel disease (IBD) has increased over the past decades. Data to support the safety of bariatric surgery (BAR) in IBD remain scarce. Our aim was to evalu...

Fateh Bazerbachi, Tarek Sawas, Eric J. Vargas, Samir Haffar… in Obesity Surgery (2018)

Article

Isolated Acute Terminal Ileitis Without Preexisting Inflammatory Bowel Disease Rarely Progresses to Crohn’s Disease

Isolated acute terminal ileitis without chronic features of inflammation poses a diagnostic challenge. Few studies have investigated the clinical significance of this entity in patients without history of infl...

Chung Sang Tse, Parakkal Deepak, Thomas C. Smyrk… in Digestive Diseases and Sciences (2017)

Article

Crohn’s disease diagnosis, treatment approach, and management paradigm: what the radiologist needs to know

Crohn’s disease is one of the major subtypes of idiopathic inflammatory bowel disease and is characterized by chronic transmural intestinal inflammation of the gastrointestinal tract anywhere from mouth to the...

Parakkal Deepak, Sang Hyoung Park, Eric C. Ehman… in Abdominal Radiology (2017)

Article

Update on the Medical Management of Crohn’s Disease

The medical management of Crohn’s disease is a rapidly evolving field with expanding therapeutic drug options and treatment strategies. In addition to corticosteroids, immunomodulators, and anti-tumor necrosis...

Parakkal Deepak, David H. Bruining in Current Gastroenterology Reports (2015)

Article

Assessing the likelihood of new-onset inflammatory bowel disease following tumor necrosis factor-alpha inhibitor therapy for rheumatoid arthritis and juvenile rheumatoid arthritis

The association between inhibition of tumor necrosis factor-alpha (TNF-α) in patients with rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) and the onset of inflammatory bowel disease (IBD) i...

Asha Krishnan, Derrick J. Stobaugh, Parakkal Deepak in Rheumatology International (2015)

Article

Ischaemic Colitis in Rheumatoid Arthritis Patients Receiving Tumour Necrosis Factor-α Inhibitors: An Analysis of Reports to the US FDA Adverse Event Reporting System

Tumour necrosis factor-α (TNF-α) inhibitors are immunosuppressants, approved for the treatment and maintenance of rheumatoid arthritis (RA). Immunosuppression has been shown to induce ischaemic colitis (IC) in...

Allison Salk, Derrick J. Stobaugh, Parakkal Deepak, Eli D. Ehrenpreis in Drug Safety (2013)

Article

Concomitant antibiotic usage does not augment the risk of inflammatory bowel disease with isotretinoin treatment for acne: a review of the Food and Drug Administration Adverse Event Reporting System

Derrick J. Stobaugh, Parakkal Deepak… in European Journal of Clinical Pharmacology (2013)